Department of Obstetrics and Gynecology, Kayseri City Hospital, Kayseri, Turkey.
Biomed Res Int. 2019 Jul 3;2019:3768601. doi: 10.1155/2019/3768601. eCollection 2019.
This study aimed to clarify the effect of gestational weight gain (GWG) on perinatal outcomes in low risk pregnancies with normal prepregnancy body mass index (BMI).
A total of 572 low-risk pregnant women with a normal prepregnancy BMI were included. GWG and inadequate or excessive weight gain were defined according to the United States Institute of Medicine updated guidelines. Adverse perinatal outcomes were compared among inadequate, normal, and excessive weight gain groups.
Of the 572 pregnant women enrolled, 62 belonged to inadequate GWG group, 80 to excessive GWG group, and 430 to normal GWG group. Maternal age, prepregnancy BMI, gravity, parity, and previous cesarean delivery rates were similar among groups. Adverse perinatal outcomes were not statistically significant among groups. Fetal weight was significantly lower in inadequate weight gain group compared to normal weight gain group (p<0.001) and fetal weight was significantly lower in normal weight gain group compared to excessive weight gain group (p<0.001). Additionally, low birth weight <2.5kgs, birth weight > 4.0kgs, and SGA and LGA rates were similar among groups ( = 0.765, = 0. 711, = 0. 702, and = 0.414, respectively). Although gestational age at delivery was term in normal percentile it was significantly lower in the inadequate weight gain group compared to others (=0.010).
This study showed that an inadequate or excessive weight gain in low-risk pregnancies with a normal prepregnancy BMI did not increase the risk of adverse perinatal outcomes.
本研究旨在明确体重增长(GWG)对正常孕前体重指数(BMI)的低危妊娠围产期结局的影响。
共纳入 572 例低危妊娠且正常孕前 BMI 的孕妇。根据美国医学研究所更新的指南,将 GWG 和不足或过度增重定义为。比较不足、正常和过度增重组之间不良围产结局的发生率。
在纳入的 572 名孕妇中,62 名属于不足 GWG 组,80 名属于过度 GWG 组,430 名属于正常 GWG 组。各组间的产妇年龄、孕前 BMI、体重指数、产次、既往剖宫产率相似。各组间不良围产结局无统计学差异。与正常体重增长组相比,不足体重增长组的胎儿体重显著降低(p<0.001),而正常体重增长组的胎儿体重显著低于过度体重增长组(p<0.001)。此外,各组间低出生体重<2.5kg、出生体重>4.0kg、SGA 和 LGA 发生率相似(=0.765、=0.711、=0.702 和=0.414)。虽然正常百分比的分娩孕周为足月,但与其他组相比,不足体重增长组的分娩孕周显著较低(=0.010)。
本研究表明,正常孕前 BMI 的低危妊娠中,增重不足或过度增重并不增加不良围产结局的风险。