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一名16岁青少年的幼年型脊柱关节炎与慢性复发性多灶性骨髓炎重叠综合征。病例报告及文献综述。

Juvenile spondyloarthritis and chronic recurrent multifocal osteomyelitis overlap syndrome in a 16-year-old adolescent. A case report and literature review.

作者信息

Znajdek Michał, Gazda Agnieszka, Gietka Piotr, Wysmołek Marta, Sudoł-Szopińska Iwona

机构信息

Department of Radiology , National Institute of Geriatrics , Rheumatology and Rehabilitation , Warsaw , Poland.

Department of Pediatrics , National Institute of Geriatrics , Rheumatology and Rehabilitation , Warsaw , Poland.

出版信息

J Ultrason. 2019;19(77):152-157. doi: 10.15557/JoU.2019.0022. Epub 2019 Jun 28.

Abstract

The authors present a very rare case of juvenile spondyloarthritis and chronic recurrent multifocal osteomyelitis overlap syndrome in a 16-year-old girl and discuss diagnostic difficulties associated with this case. Juvenile spondyloarthropathies are a type of rheumatic diseases characterized by non-symmetrical peripheral arthritis and enthesitis as well as by spondylitis. Chronic recurrent multifocal osteomyelitis is a rare, possibly autoimmune disease found primarily in children and adolescents. The disease is characterized by bone marrow inflammation and the presence of lytic and sclerotic lesions. Diagnostic imaging plays a key role in the identification of both diseases. The primary modality is X-ray; however, currently, magnetic resonance imaging and ultrasound are increasingly important. A correct early diagnosis allows one to start appropriate treatment to reduce the consequences of these diseases. The authors present a very rare case of juvenile spondyloarthritis and chronic recurrent multifocal osteomyelitis overlap syndrome in a 16-year-old girl and discuss diagnostic difficulties associated with this case. Juvenile spondyloarthropathies are a type of rheumatic diseases characterized by non-symmetrical peripheral arthritis and enthesitis as well as by spondylitis. Chronic recurrent multifocal osteomyelitis is a rare, possibly autoimmune disease found primarily in children and adolescents. The disease is characterized by bone marrow inflammation and the presence of lytic and sclerotic lesions. Diagnostic imaging plays a key role in the identification of both diseases. The primary modality is X-ray; however, currently, magnetic resonance imaging and ultrasound are increasingly important. A correct early diagnosis allows one to start appropriate treatment to reduce the consequences of these diseases.

摘要

作者报告了一例极为罕见的青少年脊柱关节炎与慢性复发性多灶性骨髓炎重叠综合征病例,患者为一名16岁女孩,并讨论了该病例相关的诊断难点。青少年脊柱关节病是一类风湿性疾病,其特征为非对称性外周关节炎、附着点炎以及脊柱炎。慢性复发性多灶性骨髓炎是一种罕见的、可能为自身免疫性的疾病,主要见于儿童和青少年。该疾病的特点是骨髓炎症以及溶骨性和硬化性病变的存在。诊断性影像学检查在这两种疾病的识别中起着关键作用。主要的检查方式是X线;然而,目前磁共振成像和超声检查越来越重要。正确的早期诊断有助于开始适当的治疗,以减轻这些疾病的后果。作者报告了一例极为罕见的青少年脊柱关节炎与慢性复发性多灶性骨髓炎重叠综合征病例,患者为一名16岁女孩,并讨论了该病例相关的诊断难点。青少年脊柱关节病是一类风湿性疾病,其特征为非对称性外周关节炎、附着点炎以及脊柱炎。慢性复发性多灶性骨髓炎是一种罕见的、可能为自身免疫性的疾病,主要见于儿童和青少年。该疾病的特点是骨髓炎症以及溶骨性和硬化性病变的存在。诊断性影像学检查在这两种疾病的识别中起着关键作用。主要的检查方式是X线;然而,目前磁共振成像和超声检查越来越重要。正确的早期诊断有助于开始适当的治疗,以减轻这些疾病的后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/166b/6750310/5d6105a88ba8/jou-19-77-152-g001.jpg

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