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石灰样胆汁(胆钙乳)与腹腔镜胆囊切除术时偶然发现的胆结石相关。

Limy bile (Milk of calcium bile) associated with gall stones discovered incidentally during laparoscopic cholecystectomy.

作者信息

Arif Sardar Hassan, Mohammed Ayad Ahmad

机构信息

Department of Surgery, College of Medicine, University of Duhok, Duhok City, Iraq.

Department of Surgery, College of Medicine, University of Duhok, Duhok City, Iraq.

出版信息

Int J Surg Case Rep. 2019;61:127-129. doi: 10.1016/j.ijscr.2019.07.032. Epub 2019 Jul 22.

DOI:10.1016/j.ijscr.2019.07.032
PMID:31357104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6664229/
Abstract

INTRODUCTION

Limy bile is very rare condition in which the gall bladder is filled with a whitish material formed mainly of calcium carbonate. It may be associated with gall stones and present with epigastric and right upper quadrant pain, fever, nausea, and jaundice. The diagnosis is easily made during radiology showing opacification of the gallbladder or the bile ducts on plain abdominal X-rays and CT-scan. Most patients are treated with cholecystectomy.

CASE PRESENTATION

A 35-year-old lady was complaining from right hypochondrial pain for 8 months. The pain was mainly at the late night and relieved with analgesics. During examination the patient had no jaundice and during abdominal examination there was deep tenderness in the right hypochonrdium. Ultrasound of the gallbladder showed evidence of multiple gall stones with bile sludge. During laparoscopic cholecystectomy the gall bladder was found to be filled with white creamy substance and multiple gall stones. The patient discharged next day with no postoperative complications.

CONCLUSION

Limy bile is a rare clinical entity of unknown etiology but obstruction of the cystic duct may be the most important step in its occurrence. The condition needs cholecystectomy as in most of the cases it is associated with gall stones. There are no reported long term sequelae and long term follows up is not recommended.

摘要

引言

石灰样胆汁是一种非常罕见的病症,胆囊中充满主要由碳酸钙形成的白色物质。它可能与胆结石有关,并表现为上腹部和右上腹疼痛、发热、恶心和黄疸。在放射学检查中,通过腹部平片和CT扫描显示胆囊或胆管显影,很容易做出诊断。大多数患者接受胆囊切除术治疗。

病例介绍

一名35岁女性主诉右季肋部疼痛8个月。疼痛主要在深夜发作,服用镇痛药后缓解。检查时患者无黄疸,腹部检查发现右季肋部有深压痛。胆囊超声显示有多个胆结石和胆泥。在腹腔镜胆囊切除术中,发现胆囊内充满白色乳状物质和多个胆结石。患者次日出院,无术后并发症。

结论

石灰样胆汁是一种病因不明的罕见临床病症,但胆囊管梗阻可能是其发生的最重要步骤。这种情况需要进行胆囊切除术,因为在大多数病例中它与胆结石有关。目前尚无长期后遗症的报道,不建议进行长期随访。

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本文引用的文献

1
Midline gallbladder makes a challenge for surgeons during laparoscopic cholecystectomy; case series of 6 patients.腹腔镜胆囊切除术时,胆囊位于中线位置给外科医生带来了挑战;6例患者的病例系列报告
Ann Med Surg (Lond). 2019 Mar 12;40:14-17. doi: 10.1016/j.amsu.2019.02.005. eCollection 2019 Apr.
2
Limy bile syndrome presenting as acute acalculous cholecystitis.表现为急性无结石性胆囊炎的石灰样胆汁综合征
BMJ Case Rep. 2019 Apr 3;12(4):e228061. doi: 10.1136/bcr-2018-228061.
3
The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines.
SCARE 2018 声明:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2018 Dec;60:132-136. doi: 10.1016/j.ijsu.2018.10.028. Epub 2018 Oct 18.
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Limy bile syndrome: review of seven cases.石灰样胆汁综合征:7例病例回顾
ANZ J Surg. 2005 Sep;75(9):787-9. doi: 10.1111/j.1445-2197.2005.03523.x.
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Management of limy bile syndrome: no therapy, laparotomy or endoscopic treatment?石灰样胆汁综合征的治疗:无需治疗、剖腹手术还是内镜治疗?
Intern Med. 2003 Jan;42(1):1-2. doi: 10.2169/internalmedicine.42.1.
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[Limy bile syndrome. Study of a case with double localization in the gallbladder and common bile duct].[石灰样胆汁综合征。胆囊和胆总管双重定位病例研究]
Gastroenterol Clin Biol. 1988 Feb;12(2):156-9.