Laboratório de Exercício Resistido e Saúde, Centro de Ciências Biológicas e da Saúde III, Universidade do Estado do Pará, Belém, Brasil.
Laboratório de Bioquímica do Exercício, Centro de Ciências Biológicas e da Saúde III, Universidade do Estado do Pará, Belém, Brasil.
Scand J Med Sci Sports. 2019 Dec;29(12):1957-1967. doi: 10.1111/sms.13528. Epub 2019 Sep 2.
Depression affects up to 40% of individuals with Parkinson's disease (PD).
To assess resistance training effects on the depressive symptoms of elderly PD patients.
A randomized control study.
Thirty-three patients (aged ≥ 60 years) were randomly divided into two groups: (a) control group: n = 16 and (b) resistance training group (RTG): n = 17. All patients with Parkinson's disease (stage 1-3 on the Hoehn and Yahr scale). The RTG, in addition to maintaining their pharmacological treatments, performed 20 weeks of resistance training. The control group maintained their pharmacological treatments. Depressive symptoms, quality of life, unified Parkinson's Disease scale, and functional capacity were evaluated in both groups.
The RTG presented a significant reduction (P < .05) of depressive symptoms (pre = 17.9 ± 8 score; post = 10.3 ± 6 score; effect size: -0.48), improved quality of life (pre = 40.3 ± 21.1 score; post = 30.2 ± 16.8 score; effect size: -0.26), and improved UPDRS (pre = 64 ± 34.6 score; post = 49.1 ± 24.1 score; effect size: -0.24). No significant changes in the control group regarding depressive symptoms (pre = 18.7 ± 5.4 score; post = 19.4 ± 5.2 score; effect size: 0.07), quality of life (pre = 39 ± 16.1 score; post = 40.6 ± 15.6 score; effect size: 0.05), and UPDRS (pre = 61.1 ± 24.3 score; post = 64.9 ± 23.4 score; effect size: 0.08) after 20 weeks.
Resistance training reduces depressive symptoms and improves the quality of life and functionality of elderly with PD.
抑郁症影响多达 40%的帕金森病（PD）患者。
评估抗阻训练对老年 PD 患者抑郁症状的影响。
随机对照研究。
33 名患者（年龄≥60 岁）被随机分为两组：（a）对照组：n=16 和（b）抗阻训练组（RTG）：n=17。所有帕金森病患者（Hoehn 和 Yahr 量表 1-3 期）。RTG 除维持药物治疗外，还进行 20 周的抗阻训练。对照组维持药物治疗。对两组患者的抑郁症状、生活质量、统一帕金森病量表和功能能力进行评估。
RTG 组抑郁症状显著降低（P<.05）（治疗前 17.9±8 分；治疗后 10.3±6 分；效应量-0.48），生活质量改善（治疗前 40.3±21.1 分；治疗后 30.2±16.8 分；效应量-0.26），UPDRS 评分改善（治疗前 64±34.6 分；治疗后 49.1±24.1 分；效应量-0.24）。对照组抑郁症状（治疗前 18.7±5.4 分；治疗后 19.4±5.2 分；效应量 0.07）、生活质量（治疗前 39±16.1 分；治疗后 40.6±15.6 分；效应量 0.05）和 UPDRS 评分（治疗前 61.1±24.3 分；治疗后 64.9±23.4 分；效应量 0.08）在 20 周后均无显著变化。
抗阻训练可减轻老年 PD 患者的抑郁症状，提高其生活质量和功能。
