Alessio Keiti O, Voss Monica, Flores Erico M M, Costa Adilson B, Duarte Fabio A, Barin Juliano S
Departamento de Tecnologia e Ciência dos Alimentos, Universidade Federal de Santa Maria, 97105-900, Santa Maria, Rio Grande do Sul, Brazil; Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, Rio Grande do Sul, Brazil.
Departamento de Tecnologia e Ciência dos Alimentos, Universidade Federal de Santa Maria, 97105-900, Santa Maria, Rio Grande do Sul, Brazil.
Talanta. 2019 Nov 1;204:266-271. doi: 10.1016/j.talanta.2019.05.091. Epub 2019 May 25.
Paper microzone plates and thermal infrared enthalpimetry (TIE) were combined with potato juice as natural reagent extract to perform the determination of hydrogen peroxide in pharmaceutical, bleaching, and toiletry products. A multichannel pipette was used for reagent addition simultaneously in multiple zones of paper devices, and the temperature rise was determined using an infrared camera. In order to provide suitable measurements, some parameters were optimized such as pH, volume of reagents, and stability of the extract. Results for the hydrogen peroxide were compared with those obtained using methods from official compendia (United States Pharmacopeia and ASTM D2180-17), with agreements ranging from 96 to 103%. The green analytical procedure index was used to compare the greenness of the proposed method with official ones, with clear advantages for TIE. Only microliters of samples and natural reagent extracts were required for analysis, and it was found that waste generation could be greatly reduced. After analysis, the paper device could be directly disposed since the final products of the reaction were O and water. According to these features, the proposed method could be considered a promising alternative to routine analysis in agreement with green analytical chemistry principles.
将纸质微区板和热红外量热法（TIE）与作为天然试剂提取物的马铃薯汁相结合，用于测定药品、漂白剂和洗漱用品中的过氧化氢。使用多通道移液器在纸质装置的多个区域同时添加试剂，并使用红外热像仪测定温度升高。为了提供合适的测量结果，对一些参数进行了优化，如pH值、试剂体积和提取物的稳定性。将过氧化氢的测定结果与使用官方药典（美国药典和ASTM D2180-17）方法获得的结果进行比较，一致性范围为96%至103%。使用绿色分析程序指数比较所提出方法与官方方法的绿色程度，TIE具有明显优势。分析仅需微升的样品和天然试剂提取物，并且发现可以大大减少废物产生。分析后，纸质装置可直接丢弃，因为反应的最终产物是氧气和水。根据这些特点，所提出的方法可被视为符合绿色分析化学原则的常规分析的一种有前景的替代方法。
