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地西他滨联合放疗治疗初诊乳腺髓系肉瘤的长期缓解

Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy.

作者信息

Minoia Carla, de Fazio Vincenza, Scognamillo Giovanni, Scattone Anna, Maggialetti Nicola, Ferrari Cristina, Guarini Attilio

机构信息

Haematology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.

Radiotherapy Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.

出版信息

Diagnostics (Basel). 2019 Jul 27;9(3):84. doi: 10.3390/diagnostics9030084.

DOI:10.3390/diagnostics9030084
PMID:31357576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6787642/
Abstract

Myeloid sarcoma (MS) represents a rare disease with an adverse clinical outcome for patients not candidate to acute myeloid leukemia (AML)-like chemotherapies. Here we present the case of an elderly patient affected by a bilateral breast localization of MS treated with the hypomethylating agent decitabine associated to radiotherapy. The association of the two treatment modalities has allowed an optimal and long-lasting disease control.

摘要

髓系肉瘤（MS）是一种罕见疾病，对于不适合接受急性髓系白血病（AML）样化疗的患者而言，其临床预后较差。在此，我们报告一例老年患者，其双侧乳腺均出现髓系肉瘤，采用去甲基化药物地西他滨联合放疗进行治疗。这两种治疗方式的联合应用实现了对疾病的最佳长期控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/09355b6cf6ae/diagnostics-09-00084-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/8c20c7ba4993/diagnostics-09-00084-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/3a380a363090/diagnostics-09-00084-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/09355b6cf6ae/diagnostics-09-00084-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/8c20c7ba4993/diagnostics-09-00084-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/3a380a363090/diagnostics-09-00084-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8189/6787642/09355b6cf6ae/diagnostics-09-00084-g003.jpg

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