Osteresch Rico, Fach Andreas, Schmucker Johannes, Eitel Ingo, Langer Harald, Hambrecht Rainer, Wienbergen Harm
Bremer Institute for Heart and Circulation Research at the Klinikum Links der Weser, 28277 Bremen, Germany.
University Heart Center, 23538 Lübeck, Germany.
J Clin Med. 2019 Jul 27;8(8):1114. doi: 10.3390/jcm8081114.
Long-term prognosis of myocardial infarction (MI) is still serious, especially in patients with MI and cardiogenic shock. To improve long-term prognosis and prevent recurrent events, sustainable cardiovascular risk factor control (RFC) after MI is crucial.
The article gives an overview on health care data regarding RFC after MI and presents recent trials on modern preventive strategies that support patients to achieve risk factor targets during long-term course.
International registry studies, such as EUROASPIRE, observed alarming deficiencies in RFC after MI. As data of the German Bremen ST-segment elevation myocardial infarction (STEMI)-Registry show, most deficiencies are found in socially disadvantaged city districts and in young patients. Several studies on prevention programmes to improve RFC after MI reported inconsistent data; however, in the recently published IPP trial a 12-months intensive prevention programme that included both repetitive personal contacts with non-physician prevention assistants and telemetric risk factor control, was associated with significant improvements of numerous risk factors (smoking, LDL and total cholesterol, systolic blood pressure and physical inactivity).
There is a strong need of action to improve long-term risk RFC after MI, especially in socially disadvantaged patients. Modern prevention programmes, using personal and telemetric contacts, have large potential to support patients in achieving long-term risk factor targets after coronary events.
心肌梗死(MI)的长期预后仍然很严峻,尤其是对于合并MI和心源性休克的患者。为改善长期预后并预防复发事件,MI后持续的心血管危险因素控制(RFC)至关重要。
本文概述了MI后RFC的医疗保健数据,并介绍了近期关于现代预防策略的试验,这些策略有助于患者在长期病程中实现危险因素目标。
国际注册研究,如EUROASPIRE,观察到MI后RFC存在令人担忧的不足。正如德国不来梅ST段抬高型心肌梗死(STEMI)注册研究的数据所示,大多数不足存在于社会经济地位不利的城市地区和年轻患者中。几项关于改善MI后RFC的预防计划的研究报告的数据并不一致;然而,在最近发表的IPP试验中,一项为期12个月的强化预防计划,包括与非医生预防助手的反复个人接触和遥测危险因素控制,与众多危险因素(吸烟、低密度脂蛋白和总胆固醇、收缩压和身体活动不足)的显著改善相关。
迫切需要采取行动改善MI后的长期RFC,尤其是在社会经济地位不利的患者中。利用个人接触和遥测接触的现代预防计划,在支持患者在冠状动脉事件后实现长期危险因素目标方面具有很大潜力。