Munday B L, Dubey J P
Mt Pleasant Laboratories, Launceston South, Tasmania.
Aust Vet J. 1988 May;65(5):150-3. doi: 10.1111/j.1751-0813.1988.tb14444.x.
Nineteen does (female goats) were dosed with 500,000 oocytes of Hammondia hammondi prior to breeding. At about 90 days of gestation these, and 18 uninoculated does were challenged with 25,000 Toxoplasma gondii oocysts. The 19 H. hammondi--inoculated does produced 26 live and one dead kid (newborn goat). The 18 does not given H. hammondi produced 12 live and 19 dead kids. However, examination of all of the kids by isolation of T. gondii in mice, serology and histology revealed that they were all infected with T. gondii. Thus, while H. hammondi "vaccination" is protective against the deleterious effects of T. gondii on pregnant does, perhaps by reducing the severity of placental lesions, it does not prevent foetal infection.
19只母山羊（雌山羊）在配种前接种了50万个哈蒙德氏巴贝斯虫卵母细胞。在妊娠约90天时，这些母山羊以及18只未接种的母山羊受到25000个刚地弓形虫卵囊的攻击。接种了哈蒙德氏巴贝斯虫的19只母山羊产下了26只活羊羔和1只死羊羔（新生山羊）。未接种哈蒙德氏巴贝斯虫的18只母山羊产下了12只活羊羔和19只死羊羔。然而，通过在小鼠中分离刚地弓形虫、血清学和组织学对所有羊羔进行检查发现，它们都感染了刚地弓形虫。因此，虽然哈蒙德氏巴贝斯虫“疫苗接种”可能通过减轻胎盘病变的严重程度来预防刚地弓形虫对怀孕母山羊的有害影响，但它并不能防止胎儿感染。
