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心脏黏液瘤所致脑动脉瘤

Cerebral Aneurysms due to Cardiac Myxoma.

作者信息

Yuan Shi-Min

机构信息

Department of Cardiothoracic Surgery, Division of Cardiac Surgery, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, Futian Province, China.

出版信息

J Coll Physicians Surg Pak. 2019 Aug;29(8):763-767. doi: 10.29271/jcpsp.2019.08.763.

Abstract

Cerebral aneurysms due to cardiac myxoma has been sporadically reported; however, the clinical features of this entity has not been fully elucidated. This meta-analysis was conducted to determine the reported clinical features and outcomes of this condition. It revealed a predominance of cardiac myxoma-related multiple fusiform aneurysms of the middle cerebral artery. The cerebral aneurysms developed at a mean of 53 months after cardiac myxoma resection. Left atrial myoxma was the most common causing cerebral aneurysm than a myxoma arising from any other sites of the heart. Most patients with myxoma-related cerebral aneurysms were under follow-up, conservative, or surgical treatments. Patients' outcomes were promising, with 69.4% (34/49) patients being stable. The overall mortality rate was 4.1% (2/49), and long-term survival seemed to be satisfactory. Cardiac myxoma resection cannot avoid the occurrence of cerebral aneurysm; therefore, cerebroimaging monitoring is recommended even after cardiac myxoma resection.

摘要

心脏黏液瘤所致脑动脉瘤已有零星报道;然而,该疾病实体的临床特征尚未完全阐明。本荟萃分析旨在确定该疾病已报道的临床特征和预后。结果显示,以大脑中动脉与心脏黏液瘤相关的多发梭形动脉瘤为主。脑动脉瘤在心脏黏液瘤切除术后平均53个月出现。左心房黏液瘤比起源于心脏其他部位的黏液瘤更常导致脑动脉瘤。大多数与黏液瘤相关的脑动脉瘤患者接受了随访、保守或手术治疗。患者预后良好,69.4%(34/49)的患者病情稳定。总死亡率为4.1%(2/49),长期生存率似乎令人满意。心脏黏液瘤切除术无法避免脑动脉瘤的发生;因此,即使在心脏黏液瘤切除术后,也建议进行脑成像监测。

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