• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[孕期及哺乳期的非营养性甜味剂]

[Non-caloric sweeteners in pregnancy and lactation].

作者信息

Cavagnari Brian M

机构信息

Escuela de Nutrición. Facultad de Ciencias de la Salud de la Pontificia Universidad Católica Argentina. Buenos Aires. Argentina.

出版信息

Rev Esp Salud Publica. 2019 Aug 2;93:e201908052.

PMID:31358725
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10308837/
Abstract

Many pregnancies have a weight gain that is higher than recommended, situation that carries several risks for the mother and her child. As a strategy to achieve a lower weight gain, the replacement of sugar-sweetened foods and beverages by those with non-caloric sweeteners could be a choice for pregnant or puerperal mothers. The objective of this article is to review the available evidence regarding the use of non-caloric sweeteners during pregnancy and lactation. Pregnancy is not a period to lose weight, so it would not be advisable to perform hypocaloric diets. However, to achieve an adequate weight gain during pregnancy, many women choose to consume food and beverages with non-caloric sweeteners. During pregnancy, the consumption of cyclamate, saccharin and crude stevia leaf should be avoided, as well as that of stevia infusions or extracts of the whole leaf. Regarding the rest of the approved non-caloric sweeteners, their consumption during pregnancy and lactation is considered to be safe, as long as they are consumed in moderation, adhering to their admissible daily intake levels. Aspartame does not reach breast milk. While saccharin, sucralose, and acesulfame-K are detectable in breast milk, their concentration is several orders of magnitude below their admissible daily intake levels.

摘要

许多孕妇体重增加超过推荐值,这种情况对母亲及其孩子有诸多风险。作为实现较低体重增加的一种策略,用含非热量甜味剂的食物和饮料替代含糖甜味的食物和饮料可能是怀孕或产后母亲的一种选择。本文的目的是综述关于孕期和哺乳期使用非热量甜味剂的现有证据。孕期不是减肥的时期,因此不宜进行低热量饮食。然而,为了在孕期实现适当的体重增加,许多女性选择食用含非热量甜味剂的食物和饮料。孕期应避免食用甜蜜素、糖精和粗制甜叶菊叶,以及甜叶菊冲泡液或全叶提取物。对于其余已批准的非热量甜味剂,只要适量食用并遵守其每日允许摄入量,在孕期和哺乳期食用被认为是安全的。阿斯巴甜不会进入母乳。虽然母乳中可检测到糖精、三氯蔗糖和安赛蜜-K,但它们的浓度比每日允许摄入量低几个数量级。

相似文献

1
[Non-caloric sweeteners in pregnancy and lactation].[孕期及哺乳期的非营养性甜味剂]
Rev Esp Salud Publica. 2019 Aug 2;93:e201908052.
2
Nonnutritive Sweeteners in Breast Milk.母乳中的非营养性甜味剂。
J Toxicol Environ Health A. 2015;78(16):1029-32. doi: 10.1080/15287394.2015.1053646. Epub 2015 Aug 12.
3
Low-calorie sweetener use and energy balance: Results from experimental studies in animals, and large-scale prospective studies in humans.低热量甜味剂的使用与能量平衡:来自动物实验研究及人类大规模前瞻性研究的结果。
Physiol Behav. 2016 Oct 1;164(Pt B):517-523. doi: 10.1016/j.physbeh.2016.04.047. Epub 2016 Apr 26.
4
Early-Life Exposure to Non-Nutritive Sweeteners and the Developmental Origins of Childhood Obesity: Global Evidence from Human and Rodent Studies.生命早期接触非营养性甜味剂与儿童期肥胖的发育起源:来自人类和啮齿动物研究的全球证据。
Nutrients. 2018 Feb 10;10(2):194. doi: 10.3390/nu10020194.
5
Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index.孕期人工甜味饮料摄入与婴儿体重指数的关系。
JAMA Pediatr. 2016 Jul 1;170(7):662-70. doi: 10.1001/jamapediatrics.2016.0301.
6
The Effect of Nonnutritive Sweeteners Added to a Liquid Diet on Volume and Caloric Intake and Weight Gain in Rats.添加到流质饮食中的非营养性甜味剂对大鼠食量、热量摄入及体重增加的影响。
Obesity (Silver Spring). 2017 Sep;25(9):1556-1563. doi: 10.1002/oby.21920. Epub 2017 Aug 1.
7
A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity.一项随机对照试验比较了 4 种低热量甜味剂和蔗糖对超重或肥胖成年人体重的影响。
Am J Clin Nutr. 2019 May 1;109(5):1288-1301. doi: 10.1093/ajcn/nqy381.
8
Consumption of non-caloric sweeteners among pregnant Chileans: a cross-sectional study.智利孕妇非热量甜味剂的消费情况:一项横断面研究。
Nutr Hosp. 2019 Aug 26;36(4):890-897. doi: 10.20960/nh.2431.
9
Consumption of non-nutritive sweeteners during pregnancy.孕期摄入非营养性甜味剂。
Am J Obstet Gynecol. 2020 Aug;223(2):211-218. doi: 10.1016/j.ajog.2020.03.034. Epub 2020 Apr 8.
10
Development and Relative Validation of a Food Frequency Questionnaire to Assess Non-Nutritive Sweeteners Intake among Pregnant Women in Santiago, Chile: A Pilot Study.开发并验证了一份用于评估智利圣地亚哥孕妇非营养性甜味剂摄入量的食物频率问卷:一项初步研究。
Nutrients. 2023 May 29;15(11):2518. doi: 10.3390/nu15112518.

引用本文的文献

1
Gestational saccharin consumption disrupts gut-brain axis glucose homeostasis control in adolescent offspring rats in a sex-dependent manner.孕期摄入糖精会以性别依赖的方式破坏青春期子代大鼠的肠-脑轴葡萄糖稳态控制。
Biol Sex Differ. 2025 Jun 16;16(1):43. doi: 10.1186/s13293-025-00724-5.

本文引用的文献

1
Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny's Metabolism and Microbiome.母亲接触非营养性甜味剂会影响后代的新陈代谢和微生物群。
Front Microbiol. 2019 Jun 20;10:1360. doi: 10.3389/fmicb.2019.01360. eCollection 2019.
2
Consumption of non-caloric sweeteners among pregnant Chileans: a cross-sectional study.智利孕妇非热量甜味剂的消费情况:一项横断面研究。
Nutr Hosp. 2019 Aug 26;36(4):890-897. doi: 10.20960/nh.2431.
3
Trends in Low-Calorie Sweetener Consumption Among Pregnant Women in the United States.美国孕妇低热量甜味剂消费趋势
Curr Dev Nutr. 2019 Jan 15;3(4):nzz004. doi: 10.1093/cdn/nzz004. eCollection 2019 Apr.
4
Non-caloric sweeteners: specific characteristics and safety assessment.非热量甜味剂:特性与安全性评估
Arch Argent Pediatr. 2019 Feb 1;117(1):e1-e7. doi: 10.5546/aap.2019.eng.e1.
5
Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies.非糖甜味剂摄入与健康结局的关联:随机和非随机对照试验及观察性研究的系统评价和荟萃分析。
BMJ. 2019 Jan 2;364:k4718. doi: 10.1136/bmj.k4718.
6
Dietary sugars and non-caloric sweeteners elicit different homeostatic and hedonic responses in the brain.饮食中的糖和无热量甜味剂会在大脑中引起不同的体内平衡和享乐反应。
Nutrition. 2019 Apr;60:80-86. doi: 10.1016/j.nut.2018.09.004. Epub 2018 Sep 13.
7
Early-Life Exposure to Non-Nutritive Sweeteners and the Developmental Origins of Childhood Obesity: Global Evidence from Human and Rodent Studies.生命早期接触非营养性甜味剂与儿童期肥胖的发育起源:来自人类和啮齿动物研究的全球证据。
Nutrients. 2018 Feb 10;10(2):194. doi: 10.3390/nu10020194.
8
Pharmacokinetics of Sucralose and Acesulfame-Potassium in Breast Milk Following Ingestion of Diet Soda.饮用无糖汽水后三氯蔗糖和乙酰磺胺酸钾在母乳中的药代动力学。
J Pediatr Gastroenterol Nutr. 2018 Mar;66(3):466-470. doi: 10.1097/MPG.0000000000001817.
9
Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies.非营养性甜味剂与心血管代谢健康:随机对照试验和前瞻性队列研究的系统评价与荟萃分析
CMAJ. 2017 Jul 17;189(28):E929-E939. doi: 10.1503/cmaj.161390.
10
Beverage Intake During Pregnancy and Childhood Adiposity.孕期饮料摄入量与儿童肥胖
Pediatrics. 2017 Aug;140(2). doi: 10.1542/peds.2017-0031. Epub 2017 Jul 8.