静脉溃疡的病因：一种新假说。
Causes of venous ulceration: a new hypothesis.
作者信息
Coleridge Smith P D, Thomas P, Scurr J H, Dormandy J A
机构信息
Bloomsbury Vascular Unit, Middlesex Hospital, London.
出版信息
Br Med J (Clin Res Ed). 1988 Jun 18;296(6638):1726-7. doi: 10.1136/bmj.296.6638.1726.
Abstract
Previous hypotheses about the causes of venous ulceration are inconsistent with recently published data. In patients with chronic venous insufficiency the number of functioning capillary loops visible in the skin on microscopy fell after the legs had been dependent for 30 minutes. Another study had shown that leucocytes became trapped in the circulation in dependent legs. A new hypothesis linking these two findings proposes that the trapped white cells occlude the capillaries and result in ischaemia of the skin of the leg.
摘要
先前关于静脉溃疡病因的假说与最近发表的数据不一致。在慢性静脉功能不全患者中，腿部下垂30分钟后，显微镜下可见的皮肤中功能正常的毛细血管袢数量减少。另一项研究表明，白细胞在下垂的腿部循环中被困住。将这两个发现联系起来的一个新假说提出，被困住的白细胞会阻塞毛细血管，导致腿部皮肤缺血。
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