Department of Radiology, University Hospitals Paris Nord Val de Seine, Beaujon, Clichy, Hauts-de-Seine, France.
INSERM U1149, Centre de Recherche Biomédicale Bichat-Beaujon, CRB3, Paris, France.
Eur Radiol. 2020 Jan;30(1):163-174. doi: 10.1007/s00330-019-06355-w. Epub 2019 Jul 29.
To assess the impact of recently developed respiratory motion correction software on contrast-enhanced cone beam CT angiography (CBCT-a) for intraprocedural image guidance during intra-arterial liver-directed therapy.
From 2015 to 2017, two groups of patients who underwent intra-arterial liver-directed therapy with (breathing, n = 30) or without (still, n = 30) significant respiratory motion artifacts were retrospectively included. All CBCT-a were processed with and without dedicated respiratory motion correction software. Four readers independently assessed the following in both reconstructions (motion correction ON and OFF): (1) overall image quality on a 0-to-5 point scale, and (2) presence of relevant peri-procedural information on tumor and vasculature (overall vessel geometry, visibility of extrahepatic vessels, target tumor conspicuity, visibility of tumor feeders).
Motion correction increased the average image quality in the breathing group from 2.0 ± 0.9 to 2.9 ± 1.0 (p < 0.01). The visibility of vessel geometry, extrahepatic vessels, and tumor feeders was significantly improved for all readers, and tumor conspicuity was improved for three readers. The average image quality was not significantly different between reconstructions in the still group (motion correction ON and OFF), for any of the readers (4.0 ± 0.6 vs 4.2 ± 0.6; p = 0.12). There was no change in the visibility of vessel geometry, extrahepatic vessels, tumor feeders, or tumor conspicuity for the four readers using the respiratory motion correction software in this group.
Using the dedicated respiratory motion correction software during intra-arterial liver-directed procedures increases the visualization of relevant peri-procedural information and image quality in CBCT-a corrupted by respiratory motion artifacts without affecting these elements in still CBCT-a.
• The use of respiratory motion correction software could reduce the need for cone beam CT angiography acquisition retake. • Motion correction software significantly increases the visibility of vessel geometry, extrahepatic vessels, and tumor feeders, as well as tumor conspicuity in cone beam CT angiography corrupted by respiratory motion artifacts. • The use of respiratory motion correction software on cone beam CT angiography uncorrupted by respiratory motion artifact does not result in decreased image quality.
评估最近开发的呼吸运动校正软件对动脉内肝定向治疗术中的对比增强锥形束 CT 血管造影（CBCT-a）的影响。
回顾性纳入 2015 年至 2017 年期间行动脉内肝定向治疗的两组患者，一组（呼吸，n=30）存在明显的呼吸运动伪影，另一组（静止，n=30）不存在明显的呼吸运动伪影。所有 CBCT-a 均使用和不使用专用呼吸运动校正软件进行处理。四位读者分别在两种重建（运动校正开和关）中评估以下内容：（1）0 到 5 分的整体图像质量，以及（2）肿瘤和血管的相关围手术期信息的存在（整体血管几何形状、肝外血管的可见性、靶肿瘤显著性、肿瘤供养血管的可见性）。
运动校正将呼吸组的平均图像质量从 2.0±0.9 提高到 2.9±1.0（p<0.01）。对于所有读者，血管几何形状、肝外血管和肿瘤供养血管的可见性均显著改善，三位读者的肿瘤显著性也得到改善。在静止组，任何一位读者的重建之间（运动校正开和关）的平均图像质量均无显著差异（4.0±0.6 vs 4.2±0.6；p=0.12）。对于四位读者，使用呼吸运动校正软件时，血管几何形状、肝外血管、肿瘤供养血管和肿瘤显著性的可见性均未发生变化。
在动脉内肝定向治疗过程中使用专用呼吸运动校正软件可增加 CBCT-a 中受呼吸运动伪影影响的相关围手术期信息和图像质量的可视化，而不会影响静止 CBCT-a 中的这些元素。
呼吸运动校正软件的使用可能减少对锥形束 CT 血管造影采集重拍的需求。
运动校正软件可显著提高受呼吸运动伪影影响的锥形束 CT 血管造影中血管几何形状、肝外血管和肿瘤供养血管的可见性以及肿瘤显著性。
在不受呼吸运动伪影影响的锥形束 CT 血管造影上使用呼吸运动校正软件不会导致图像质量下降。
