支气管镜活检印片在肺部肿瘤中的评估：细胞组织学相关性研究
Evaluation of Imprint Smears of Bronchoscopic Biopsy in Lung Tumors: A Cytohistological Correlation.
作者信息
Chowdhury Abhishek
机构信息
Department of Pathology, IPGME and R, Kolkata, West Bengal, India.
出版信息
J Cytol. 2019 Jul-Sep;36(3):157-159. doi: 10.4103/JOC.JOC_122_18.
BACKGROUND
There are several methods for obtaining samples in patients of lung tumors, of which bronchoscopic biopsy is the most common. In most of Indian scenario, however, histopathology diagnosis is time taking.
AIMS AND OBJECTIVES
To evaluate imprint cytology as a tool for rapid diagnosis of lung carcinoma and its histopathological correlation.
STUDY TYPE
Prospective study on accuracy of a diagnostic test.
MATERIALS AND METHODS
A total of 175 cases were included in the study, and all of them were subjected to brochoscopic biopsy. Imprint smears were prepared from all the bronchoscopy specimens obtained from 175 cases. Imprint smears were stained with Leishman-Giemsa cocktail and Pap stain, and histopathology sections were stained with hematoxlin and eosin. Histopathological findings were confirmed by immunohistochemistry.
RESULTS
Sensitivity and specificity of imprint cytology was 84.9% and 72.4%, respectively when compared to histopathology as standard.
CONCLUSION
Imprint cytology can be used as a preliminary tool for diagnosis in lung tumor bronchoscopic biopsies.
背景
在肺肿瘤患者中获取样本有多种方法，其中支气管镜活检最为常见。然而，在印度的大多数情况下，组织病理学诊断耗时较长。
目的
评估印片细胞学作为快速诊断肺癌及其组织病理学相关性的工具。
研究类型
关于诊断试验准确性的前瞻性研究。
材料与方法
本研究共纳入175例病例，所有病例均接受支气管镜活检。从175例患者获得的所有支气管镜标本制备印片涂片。印片涂片用利什曼-吉姆萨混合染液和巴氏染色法染色，组织病理学切片用苏木精和伊红染色。组织病理学结果通过免疫组织化学得到证实。
结果
与作为标准的组织病理学相比，印片细胞学的敏感性和特异性分别为84.9%和72.4%。
结论
印片细胞学可作为肺肿瘤支气管镜活检诊断的初步工具。
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