Chowdhry Mohit, Agrawal Soma, Thakur Uday Kumar
Department of Transfusion Medicine, Indraprastha Apollo Hospitals, New Delhi, India.
Asian J Transfus Sci. 2019 Jan-Jun;13(1):54-56. doi: 10.4103/ajts.AJTS_26_18.
Anti-Hro is an alloantibody produced in individuals with -D- phenotype after a sensitizing event. Owing to the rarity of this antigen negative unit, registration in rare donor registries helps in procuring blood components at the earliest. We had a patient of -D- with anti-Hro antibody who required 7 units of red cells which was unavailable at our center. The patients near relatives were typed in search of a similar phenotype blood. Search was made for the rare units and Japanese Red Cross Society, American Red Cross Society, and International Blood Group Reference Laboratory, United Kingdom was contacted. Patient's brother and mother were typed as -D- and one unit from each of them was collected, irradiated, and transfused to the patient. Five units were imported from the Japanese Red Cross Society, Japan. Accessibility for identification and confirmation of rare blood groups and provision of the same can be centralized and liaison with the international registries can go a long way in the provision of blood components at the earliest.
抗Hro是-D-表型个体在致敏事件后产生的一种同种抗体。由于这种抗原阴性血型单位非常罕见，在稀有献血者登记处登记有助于尽早获取血液成分。我们有一名携带抗Hro抗体的-D-患者，他需要7个单位的红细胞，但我们中心没有。对患者的近亲进行血型检测以寻找相似表型的血液。寻找稀有血型单位，并联系了日本红十字会、美国红十字会和英国国际血型参考实验室。患者的兄弟和母亲血型为-D-，从他们每人身上采集了一个单位的血液，经过辐照后输给了患者。另外五个单位的血液从日本红十字会进口。稀有血型的识别、确认及供应的可及性可以集中化，与国际登记处的联络对于尽早供应血液成分大有帮助。
