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全喉切除术联合咽食管切除术的水平机械封闭术:老年患者有效性评估

Total Laryngectomy with Horizontal Mechanical Closure of the Pharyngoesophagectomy: Evaluation of the Effectiveness in Elderly Patients.

作者信息

Allegra Eugenia, Mantia Ignazio La, Azzolina Alfio, Natale Massimo De, Trapasso Serena, Saita Vincenzo

机构信息

Otolaryngology Unit, Department of Health Science, Magna Graecia University of Catanzaro, Catanzaro, Italy.

Otolaryngology Unit, Santa Marta e Santa Venera Hospital, Acireale, Catania, Italy.

出版信息

Int Arch Otorhinolaryngol. 2019 Jul;23(3):e338-e342. doi: 10.1055/s-0039-1685155. Epub 2019 May 28.

Abstract

The main modalities of surgical treatment for laryngeal cancer include transoral laser microsurgery (TLM), open preservation surgery, and total laryngectomy (TL). In the elderly, for the presence of comorbidities, the surgical approach more appropriate in many cases remains TL. The use of a stapler for the closure of the esophagus has been introduced to reduce surgical time and postoperative complications such as pharyngocutaneous fistula (PCF).  In the present study, we have evaluated the effectiveness of the use of the horizontal mechanical pharyngoesophageal closure in patients who underwent TL.  This nonrandomized study was performed on consecutive patients with histopathologically proven squamous cell endolaryngeal carcinoma. The TL was performed using a linear stapler to mechanically suture the pharyngotomy using the semiclosed technique.  A total of 33 patients underwent TL, and 13 of them underwent neck dissection. A total of 15 patients (45.4%) were ≤70 years old, and 18 were > 70 years old. Analyzing the results in relation to age, patients > 70 years old showed tumors at an earlier stage than those aged ≤70 years old. Furthermore, in this group there was a greater number of patients who had comorbidities (  = 0.014). In total, we had 2 (6%) cases of PCF in 6.6% in the group ≤70 years old, and in 5.5% of the group > 70 years old (  = 1.00).  The use of the stapler for the horizontal closure of the pharyngoesophagectomy in the patients subjected to TL is proven to be useful and safe even when used in elderly patients.

摘要

喉癌的主要手术治疗方式包括经口激光显微手术(TLM)、开放性保留手术和全喉切除术(TL)。对于老年人,由于存在合并症,在许多情况下更合适的手术方式仍是TL。为了减少手术时间和术后并发症,如咽皮肤瘘(PCF),已引入使用吻合器关闭食管。在本研究中,我们评估了在接受TL的患者中使用水平机械性咽食管闭合术的有效性。

这项非随机研究是对组织病理学证实为喉鳞状细胞癌的连续患者进行的。使用线性吻合器进行TL,采用半闭合技术机械缝合咽切开术。

共有33例患者接受了TL,其中13例接受了颈部清扫术。共有15例患者(45.4%)年龄≤70岁,18例年龄>70岁。分析与年龄相关的结果,年龄>70岁的患者肿瘤分期早于年龄≤70岁的患者。此外,在该组中合并症患者数量更多(P = 0.014)。总体而言,年龄≤70岁组中有2例(6%)发生PCF,占该组的6.6%,年龄>70岁组中有5.5%发生PCF(P = 1.00)。

在接受TL的患者中,使用吻合器进行咽食管切除术的水平闭合被证明是有用且安全的,即使在老年患者中使用也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c11f/6660295/696ea8ec2080/10-1055-s-0039-1685155-i0843or-1.jpg

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