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印度一家三级癌症中心对喉癌喉切除术后吻合器闭合术的评估。

Evaluation of stapled closure following laryngectomy for carcinoma larynx in an Indian tertiary cancer centre.

作者信息

Babu S, Varghese B T, Iype E M, George P S, Sebastian P

机构信息

Department of Surgical Oncology, Regional Cancer Centre, Trivandrum, India.

出版信息

Indian J Cancer. 2015 Jul-Sep;52(3):376-80. doi: 10.4103/0019-509X.176728.

Abstract

BACKGROUND AND AIM

Stapling devices are used for pharyngeal closure after laryngectomy for the past few decades although it has not gained wide acceptance. This study is aimed at evaluating the role of stapler in pharyngeal closure after laryngectomy.

METHODS

Thirty consecutive patients who underwent stapled laryngectomy at our institution from October 2004 to February 2008 were evaluated retrospectively. Linear stapler (Proximate TX 60; Ethicon Inc.) was used for closure of neopharynx.

RESULTS

There were 28 males and 2 females with mean age of 54.5 years (54.5 ± 11.2). Nineteen of these patients (63.3%) had salvage laryngectomy and two patients (6.7%) had laryngectomy for a second primary tumor. Twenty-eight patients had total laryngectomy (TL), whereas two had extended TL. Eight patients had salivary leak (26.7%). Of these, 6 (75%) had prior radiation. All salivary leaks except one were managed conservatively. Follow-up ranged from 7 to 54 months (median: 21 months). Seven patients (23.3%) developed recurrence, six at the stoma, of which 5 (83.3%) had initial extension of disease to the subglottis. Four-year disease-free survival was 54.4%.

CONCLUSION

Pharyngeal closure by linear stapler is an efficient and safe method of fashioning the neopharynx after laryngectomy with no added risk of occurrence of pharyngocutaneous fistula in primary and salvage laryngectomies.

摘要

背景与目的

在过去几十年里,吻合器一直用于喉切除术后的咽闭合术,尽管它尚未得到广泛认可。本研究旨在评估吻合器在喉切除术后咽闭合术中的作用。

方法

回顾性评估了2004年10月至2008年2月在我院接受吻合器辅助喉切除术的30例连续患者。使用直线吻合器(Proximate TX 60;爱惜康公司)闭合下咽。

结果

男性28例,女性2例,平均年龄54.5岁(54.5±11.2)。其中19例患者(63.3%)接受了挽救性喉切除术,2例患者(6.7%)因第二原发肿瘤接受了喉切除术。28例患者行全喉切除术(TL),2例行扩大全喉切除术。8例患者发生唾液漏(26.7%)。其中,6例(75%)曾接受过放疗。除1例唾液漏外,其余均采用保守治疗。随访时间为7至54个月(中位数:21个月)。7例患者(23.3%)出现复发,6例发生在造口处,其中5例(83.3%)疾病最初侵犯至声门下。4年无病生存率为54.4%。

结论

直线吻合器进行咽闭合术是喉切除术后构建下咽的一种有效且安全的方法,在初次和挽救性喉切除术中不会增加咽皮肤瘘发生的风险。

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