Ahmadi Firoozeh, Moukhah Somayeh, Hosseini Roya, Maghari Amirhossein
Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, Tehran, Iran.
Department of Reproductive Health, Nursing and Midwifery Faculty, Tehran University of Medical Sciences, Tehran, Iran.
Oman Med J. 2019 Jul;34(4):308-312. doi: 10.5001/omj.2019.61.
Ultrasonography is a noninvasive and safe modality for assessing body fat and is routinely performed in developed countries. Although pregnant women with obesity are at risk for many unfavorable outcomes, the relationship between abdominal fat distribution and metabolic syndrome (MS) is evident in some studies. Therefore, it is important to evaluate fat thickness in non-obese women and predict MS using fat thickness measurement.
A total of 132 pregnant women completed anthropometric and demographic questionnaires. All women were scanned for visceral fat thickness (VFT) via ultrasound at 11-14 weeks gestation. Body mass index (BMI) and waist circumference (WC) were calculated at the first prenatal visit. MS components were also measured in the same weeks.
MS was detected in seven (5.3%) women. There was a statistically significant difference between women with and without MS for weight, WC, anterior and posterior VFT, insulin, lipid profile (total cholesterol, high-density lipoprotein cholesterol, and triglyceride), and systolic and diastolic blood pressure ( < 0.050). The optimal cut-off points determined for predicting MS disorder were an anterior VFT of 43.83 mm and a posterior VFT of 32.50 mm.
Fat thickness measurement in the first trimester is a good predictor for MS even in women with a normal BMI. Ultrasonography as a safe, simple, and cost-effective modality can be used to assess fat thickness besides the other screening evaluations in the first trimester of pregnancy.
超声检查是一种用于评估身体脂肪的非侵入性且安全的方法，在发达国家已常规开展。尽管肥胖孕妇面临许多不良结局的风险，但一些研究表明腹部脂肪分布与代谢综合征（MS）之间存在关联。因此，评估非肥胖女性的脂肪厚度并通过测量脂肪厚度预测MS具有重要意义。
共有132名孕妇完成了人体测量和人口统计学问卷。所有女性在妊娠11 - 14周时通过超声扫描测量内脏脂肪厚度（VFT）。在首次产前检查时计算体重指数（BMI）和腰围（WC）。在同一孕周还测量了MS的各项指标。
7名（5.3%）女性被检测出患有MS。患有和未患有MS的女性在体重、WC、前后VFT、胰岛素、血脂谱（总胆固醇、高密度脂蛋白胆固醇和甘油三酯）以及收缩压和舒张压方面存在统计学显著差异（<0.050）。预测MS紊乱的最佳切点为前VFT 43.83 mm和后VFT 32.50 mm。
即使对于BMI正常的女性，孕早期测量脂肪厚度也是MS的良好预测指标。超声检查作为一种安全、简单且经济有效的方法，除了用于孕早期的其他筛查评估外，还可用于评估脂肪厚度。
