Dos Prazeres Tavares Hamilton, Dos Santos Débora Cristina Damasceno Meirelles, Abbade Joelcio Francisco, Negrato Carlos Antonio, de Campos Paulo Adão, Calderon Iracema Mattos Paranhos, Rudge Marilza Vieira Cunha
Department of Gynecology and Obstetrics, Botucatu Medical School, UNESP-Univ Estadual Paulista, Botucatu, São Paulo Brazil.
Department of Gynecology and Obstetrics, Medical School, University Agostinho Neto (UAN), Luanda, Angola.
Diabetol Metab Syndr. 2016 Mar 22;8:27. doi: 10.1186/s13098-016-0139-3. eCollection 2016.
Metabolic syndrome (MetS) is a cluster of risk factors for type 2 diabetes (Type2 DM) and cardiovascular diseases (CVD), and its prevalence varies based on region, population, and sex. Newborns of women with MetS have a greater risk of adverse perinatal outcomes. This study explores the prevalence of metabolic syndrome in non-diabetic, pregnant Angolan women and the adverse perinatal outcomes associated with it.
This cross-sectional study collected the demographic, anthropometric and clinical data of 675 pregnant women in the maternity ward of General Hospital in Huambo, Angola. Metabolic syndrome was defined using four criteria: the third report of the National Cholesterol Education Program Adult Treatment Panel (ATPIII), the Joint Interim Statement (JIS), and definitions by both Bartha et al. and Chatzi et al.
The crude prevalence of metabolic syndrome was 36.6 % based on the JIS definition, 29.2 % based on NCEP ATPIII, 12.6 % based on Chatzi et al. and 1.8 % based on Bartha et al. In general, the prevalence of adverse perinatal outcomes was 14.1 %.
There was a high prevalence of metabolic syndrome, depending on the criteria used, and thus a great need to harmonize the criteria and cutoff points. Perinatal adverse outcomes were higher in pregnant women with metabolic syndrome.
代谢综合征（MetS）是2型糖尿病（Type2 DM）和心血管疾病（CVD）的一组危险因素，其患病率因地区、人群和性别而异。患有代谢综合征的女性所生新生儿出现围产期不良结局的风险更高。本研究探讨了安哥拉非糖尿病孕妇代谢综合征的患病率及其相关的围产期不良结局。
这项横断面研究收集了安哥拉万博总医院产科病房675名孕妇的人口统计学、人体测量学和临床数据。代谢综合征采用四项标准进行定义：美国国家胆固醇教育计划成人治疗小组第三次报告（ATPIII）、联合临时声明（JIS）以及Bartha等人和Chatzi等人的定义。
根据JIS定义，代谢综合征的粗患病率为36.6%；根据NCEP ATPIII为29.2%；根据Chatzi等人的定义为12.6%；根据Bartha等人的定义为1.8%。总体而言，围产期不良结局的患病率为14.1%。
根据所使用的标准，代谢综合征的患病率较高，因此非常需要统一标准和切点。患有代谢综合征的孕妇围产期不良结局发生率更高。
