Wozniak Bartosz, Tin Sergey, de Vries Johannes G
Leibniz-Institut für Katalyse e.V. , Universität Rostock , Albert-Einstein-Str.29a , 18059 Rostock , Germany . Email:
Chem Sci. 2019 Jun 6;10(24):6024-6034. doi: 10.1039/c9sc01309a. eCollection 2019 Jun 28.
The limits to the supply of fossil resources and their ever increasing use forces us to think about future scenarios for fuels and chemicals. The platform chemical 5-hydroxymethyl-furfural (HMF) can be obtained from biomass in good yield and has the potential to be converted in just a few steps into a multitude of interesting products. Over the last 20 years, the conversion of HMF to 1-hydroxyhexane-2,5-dione (HHD) has been studied by several groups. It is possible to convert HMF into HHD by hydrogenation/hydrolytic ring opening reaction in aqueous phase using various heterogeneous and homogeneous catalysts. This review addresses both the state of the art of HHD synthesis, including mechanistic aspects of its formation, as well as the recent progress in the application of HHD as a building block for many useful chemicals including pyrroles, cyclopentanone derivatives and triols.
化石资源供应的限制及其不断增加的使用迫使我们思考燃料和化学品的未来情景。平台化学品5-羟甲基糠醛（HMF）可以从生物质中高产率地获得，并且有可能在短短几步内转化为多种有趣的产品。在过去20年中，几个研究小组对HMF转化为1-羟基己烷-2,5-二酮（HHD）进行了研究。使用各种多相和均相催化剂，通过水相中的氢化/水解开环反应可以将HMF转化为HHD。本综述既讨论了HHD合成的现状，包括其形成的机理方面，也讨论了HHD作为许多有用化学品（包括吡咯、环戊酮衍生物和三醇）的基础原料应用的最新进展。
