Xia Haian, Xu Siquan, Hu Hong, An Jiahuan, Li Changzhi
Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-forest Biomass China
School of Chemical Engineering, Nanjing Forestry University Nanjing 210037 China.
RSC Adv. 2018 Sep 3;8(54):30875-30886. doi: 10.1039/c8ra05308a. eCollection 2018 Aug 30.
5-hydroxymethylfurfural (HMF) is a very important versatile platform compound derived from renewable biomass. The functionalized molecule with an aldehyde group, a hydroxyl group and a furan ring provides great potential for the production of a wide variety of valuable chemicals. This review highlights the latest advances in the catalytic conversion of HMF into value-added chemicals by some important reactions including (1) aerobic oxidation of HMF into furan-based aldehydes and acids such as 5-hydroxymethyl-2-furancarboxylic acid (HMFCA), 2,5-diformylfuran (DFF), and furandicarboxylic acid (FDCA), (2) reductive amination of HMF to amine, (3) the synthesis of aromatics by Diels-alder reaction followed by a dehydration reaction, (4) catalytic reduction of HMF into 2,5-bis(hydroxymethyl)furan (BHMF), and 2,5-dimethyl furan (DMF), (5) catalytic oxidation of HMF into maleic anhydride, and some other important transformations. The review mainly focuses on the recent progress in bio-catalytic, electrocatalytic, and heterogeneous catalytic transformation of HMF into high value chemicals over the past few years. Moreover, an outlook is provided to highlight opportunities and challenges related to this hot research topic.
5-羟甲基糠醛（HMF）是一种非常重要的源自可再生生物质的多功能平台化合物。这种具有醛基、羟基和呋喃环的功能化分子为生产多种有价值的化学品提供了巨大潜力。本文综述重点介绍了通过一些重要反应将HMF催化转化为增值化学品的最新进展，这些反应包括：（1）将HMF有氧氧化为基于呋喃的醛和酸，如5-羟甲基-2-呋喃甲酸（HMFCA）、2,5-二甲基呋喃（DFF）和呋喃二甲酸（FDCA）；（2）将HMF还原胺化生成胺；（3）通过狄尔斯-阿尔德反应随后脱水反应合成芳烃；（4）将HMF催化还原为2,5-双（羟甲基）呋喃（BHMF）和2,5-二甲基呋喃（DMF）；（5）将HMF催化氧化为马来酸酐，以及其他一些重要的转化反应。本文综述主要聚焦于过去几年中HMF在生物催化、电催化和多相催化转化为高价值化学品方面的最新进展。此外，还展望了这一热门研究课题相关的机遇和挑战。
