Şahin Hilal, Akdoğan Aslı Irmak, Ayaz Duygu, Karadeniz Tuğba, Sancı Muzaffer
University of Health Sciences, Tepecik Training and Research Hospital, Clinic of Radiology, İzmir, Turkey.
University of Health Sciences, Tepecik Training and Research Hospital, Clinic of Pathology, İzmir, Turkey.
Turk J Obstet Gynecol. 2019 Jun;16(2):118-123. doi: 10.4274/tjod.galenos.2019.67209. Epub 2019 Jul 3.
To evaluate the incidence of the "floating ball" sign in cross-sectional imaging modalities in patients with ovarian teratoma, and to investigate the relationship between the morphologic features of the teratoma and this sign.
Preoperative computed tomography and magnetic resonance imaging studies of 112 women with a pathologic diagnosis of ovarian mature cystic teratoma (MCT) were reviewed for the presence of the floating ball sign. Tumor size, tumor characteristics and the number, size, and characteristics of floating globules were evaluated.
In 112 patients (mean age 35.5±16 years, range 5-84 years), 118 ovarian MCTs were diagnosed pathologically. The floating ball sign was demonstrated in cross-sectional imaging in 30 (25.4%) patients. Among 2 of them, MCT was associated with malignancy (squamous cell carcinoma). There was a significant relationship between the floating ball sign, tumor size, and the wall thickness of the tumor (p=0.003 and p=0.018, respectively). In linear regression analysis, a similarly significant relationship was found between the presence of this sign and tumor size and patient age (p=0.003 and p=0.035, respectively).
The floating ball sign, as a pathognomonic sign for the diagnosis of ovarian teratomas, seems to be more common than is known. Although this sign is almost always seen in MCTs, it may rarely be seen in teratomas with malignant transformation. The relationship of this sign with the characteristics of the tumor can provide an insight into the occurrence of these balls.
评估卵巢畸胎瘤患者在横断面成像模式下“浮球”征的发生率，并研究畸胎瘤形态特征与该征象之间的关系。
回顾性分析112例经病理诊断为卵巢成熟囊性畸胎瘤（MCT）的女性患者的术前计算机断层扫描和磁共振成像研究，以观察浮球征的存在情况。评估肿瘤大小、肿瘤特征以及漂浮小球的数量、大小和特征。
112例患者（平均年龄35.5±16岁，范围5 - 84岁）经病理诊断为118个卵巢MCT。30例（25.4%）患者在横断面成像中显示浮球征。其中2例MCT与恶性肿瘤（鳞状细胞癌）相关。浮球征与肿瘤大小及肿瘤壁厚度之间存在显著关系（分别为p = 0.003和p = 0.018）。在线性回归分析中，该征象的存在与肿瘤大小及患者年龄之间也发现了类似的显著关系（分别为p = 0.003和p = 0.035）。
浮球征作为诊断卵巢畸胎瘤的特征性征象，似乎比已知情况更为常见。虽然此征象几乎总是在MCT中出现，但在发生恶变的畸胎瘤中可能很少见。该征象与肿瘤特征的关系可为这些小球的形成提供深入了解。
