Al Hilli Fayek, Ansari Naseem
Department of Pathology, Salmaniya Medical Complex, Bahrain.
Int J Gynecol Pathol. 2006 Oct;25(4):347-53. doi: 10.1097/01.pgp.0000209576.46834.34.
Ovarian cystic teratomas with intracystic balls are rare, and only 11 cases have been reported since 1946. We present 2 new cases and review the literature for the clinical presentation and morphological appearances of the cysts and balls. We also present our histology findings on a third case reported in the international literature. The pathogenesis of balls formation is unknown. We put forward a hypothesis based on the forces which control the production and absorption of the intracystic contents and also recommendations for investigators who may encounter this lesion. We believe that predominance of large secretory and absorptive rather than exfoliative surfaces lining the cysts would favor the absorption of most of the contents into the general circulation, leaving the remaining material to solidify and mould into balls. Still, however, there are many unanswered questions.
伴有囊内球体的卵巢囊性畸胎瘤很罕见，自1946年以来仅报道过11例。我们报告2例新病例，并回顾文献中关于囊肿及球体的临床表现和形态学表现。我们还展示了国际文献中报道的第三例病例的组织学发现。球体形成的发病机制尚不清楚。我们基于控制囊内物质产生和吸收的力量提出一个假说，并为可能遇到此病变的研究者提供建议。我们认为，囊肿内衬的主要是大的分泌和吸收表面而非剥脱表面，这有利于大部分内容物吸收进入体循环，使剩余物质凝固并塑形成球体。然而，仍然存在许多未解答的问题。
