Yildirim Metin, Belli Seyda, Ozsoy Sule, Taskin Umit
Department of Otorhinolaryngology, Bagcilar Training and Research Hospital, Istanbul, Turkey.
Department of Pathology, Bagcilar Training and Research Hospital, Istanbul, Turkey, India.
Indian J Pathol Microbiol. 2019 Jul-Sep;62(3):454-456. doi: 10.4103/IJPM.IJPM_555_18.
Simultaneously triple head and neck malignancies are extremely rare. We report a case who had epithelial and mesenchymal malignant tumor with lymphoid malignancy in head and neck area. A patient who is 74 year old male patient presented to the otorhinolaryngology department with severe breathing difficulty due to laryngeal mass. The result of laryngeal biopsy was invasive SCCs, so patient underwent total larygectomy and bilateral level 2,3,4 neck disection operation. Primary 3 different type head and neck tumors were observed with histopathological examination. These were orderly invasive SCCs in larynx, B-cell Non-Hodgkin's lymphoma in tongue root and one lymph node of left neck dissection material, Kaposi's sarcoma in one lymph node of right neck dissection material. Although synchronous head and neck tumors occurs very rare with laryngeal carcinoma, the neck dissection materials should be researched for synchronous tumors.
同时发生的头颈部三重恶性肿瘤极为罕见。我们报告一例头颈部区域患有上皮性和间叶性恶性肿瘤以及淋巴恶性肿瘤的病例。一名74岁男性患者因喉部肿物导致严重呼吸困难就诊于耳鼻喉科。喉部活检结果为浸润性鳞状细胞癌，因此患者接受了全喉切除术及双侧2、3、4区颈部清扫术。组织病理学检查发现原发性3种不同类型的头颈部肿瘤。这些肿瘤依次为喉部浸润性鳞状细胞癌、舌根及左侧颈部清扫标本中的一个淋巴结的B细胞非霍奇金淋巴瘤、右侧颈部清扫标本中的一个淋巴结的卡波西肉瘤。尽管喉癌同时发生头颈部肿瘤非常罕见，但对于同步肿瘤仍应检查颈部清扫标本。
