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四重原发性多发性恶性肿瘤：通过食管胃十二指肠镜检查/结肠镜检查早期发现第二原发性恶性肿瘤对经典型卡波西肉瘤患者至关重要。

Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi's Sarcoma.

作者信息

Maruyama Nobuyuki, Okubo Yuko, Umikawa Masato, Matsuzaki Akiko, Hokama Akira, Hirano Fusahiro, Maruyama Tessho, Nishihara Kazuhide, Nakasone Toshiyuki, Makishi Shoko, Nakamura Hiroyuki, Yoshimi Naoki

机构信息

Department of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan.

Department of Dermatology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan.

出版信息

Diagnostics (Basel). 2020 Apr 14;10(4):218. doi: 10.3390/diagnostics10040218.

DOI:10.3390/diagnostics10040218
PMID:32295165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7235704/
Abstract

Currently, Kaposi's sarcoma (KS) is treated following the recommendations of international guidelines. These guidelines recommend esophagogastroduodenoscopy/colonoscopy for detecting multicentric KS of visceral lesions. Second primary malignancies (SPMs) are also a common KS complication; however, information on their detection and treatment is unfortunately not yet indicated in these guidelines. This paper reports on an 86-year-old man who suffered from quadruple primary malignancies: skin classic KS with colon adenocarcinoma, oral squamous cell carcinoma (maxilla), and well-differentiated stomach adenocarcinoma. Gastric cancer was incidentally detected during esophagogastroduodenoscopy, which was performed to detect visceral KS. We suggest that esophagogastroduodenoscopy/colonoscopy be routinely performed during the follow-up of patients with KS. As SPMs are crucial complications in patients with KS, these malignancies should be detected as early as possible.

摘要

目前，卡波西肉瘤（KS）的治疗遵循国际指南的建议。这些指南推荐进行食管胃十二指肠镜检查/结肠镜检查以检测内脏病变的多中心KS。第二原发性恶性肿瘤（SPM）也是KS的常见并发症；然而，遗憾的是这些指南中尚未提及关于其检测和治疗的信息。本文报道了一名86岁男性，他患有四重原发性恶性肿瘤：皮肤经典型KS伴结肠腺癌、口腔鳞状细胞癌（上颌）和高分化胃腺癌。在为检测内脏KS而进行的食管胃十二指肠镜检查中偶然发现了胃癌。我们建议在KS患者的随访期间常规进行食管胃十二指肠镜检查/结肠镜检查。由于SPM是KS患者的关键并发症，应尽早检测出这些恶性肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/250d58451219/diagnostics-10-00218-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/2f89a03abe88/diagnostics-10-00218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/eb7559400fae/diagnostics-10-00218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/250d58451219/diagnostics-10-00218-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/2f89a03abe88/diagnostics-10-00218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/eb7559400fae/diagnostics-10-00218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8091/7235704/250d58451219/diagnostics-10-00218-g003.jpg

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