Author Affiliations: School of Nursing, Li Ka Shing Faculty of Medicine, the University of Hong Kong (Ms Ho, Dr Li, Dr Ho, Ms Cheung, and Dr Chung); Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong (Dr Chan); and Paediatric Oncology Unit, Queen Mary Hospital (Ms Chiu), Hong Kong, China.
Cancer Nurs. 2020 Nov/Dec;43(6):446-454. doi: 10.1097/NCC.0000000000000736.
Evidence shows that survivors of solid tumors have a lower survival rate and shorter disease-free survival time than survivors of leukemia. However, the psychological well-being and health-related quality of life (HRQOL) of these 2 groups of cancer survivors have not been compared.
To examine and compare the impact of cancer and treatment-related effects on psychological well-being and HRQOL between survivors of childhood solid tumors and leukemia.
We conducted a cross-sectional study involving 65 Hong Kong survivors of solid tumors and 70 survivors of leukemia aged 8 to 18 years who had their medical follow-up in a pediatric outpatient clinic. Participants' depressive symptoms, self-esteem, and HRQOL were assessed. Twenty-two survivors of childhood solid tumors and 15 survivors of childhood leukemia were then selected for semistructured interviews.
Survivors of childhood solid tumors reported significantly higher mean scores for depressive symptoms, and lower mean self-esteem and HRQOL scores than survivors of childhood leukemia. Qualitative data revealed that survivors of childhood solid tumors faced more challenges in their daily life than survivors of childhood leukemia.
Survivors of childhood solid tumors reported poorer psychological well-being and HRQOL than survivors of childhood leukemia. This vulnerable group warrants more attention and support.
It is vital for healthcare professionals to understand the impact of cancer and treatment-related effects in the context of different types of cancer. This will facilitate development and evaluation of appropriate psychological interventions to promote psychological well-being and HRQOL among childhood cancer survivors.
有证据表明，实体瘤幸存者的生存率和无病生存期均短于白血病幸存者。然而，这两组癌症幸存者的心理健康状况和健康相关生活质量（HRQOL）尚未进行比较。
探讨和比较儿童实体瘤幸存者与白血病幸存者的癌症和治疗相关影响对心理健康和 HRQOL 的影响。
我们进行了一项横断面研究，纳入了在儿科门诊接受医疗随访的 65 名香港儿童实体瘤幸存者和 70 名儿童白血病幸存者，评估了他们的抑郁症状、自尊和 HRQOL。然后选择 22 名儿童实体瘤幸存者和 15 名儿童白血病幸存者进行半结构式访谈。
儿童实体瘤幸存者的抑郁症状评分显著较高，自尊和 HRQOL 评分显著较低。定性数据显示，儿童实体瘤幸存者在日常生活中面临的挑战比儿童白血病幸存者更多。
儿童实体瘤幸存者报告的心理健康状况和 HRQOL 均差于儿童白血病幸存者。这一弱势群体需要更多的关注和支持。
医护人员了解不同类型癌症的癌症和治疗相关影响至关重要。这将有助于制定和评估适当的心理干预措施，以促进儿童癌症幸存者的心理健康和 HRQOL。
