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酒精使用障碍及共病抑郁:一项随机对照试验,旨在探究支持性短信在辅助康复方面的有效性。

Alcohol Use Disorder and Comorbid Depression: A Randomized Controlled Trial Investigating the Effectiveness of Supportive Text Messages in Aiding Recovery.

机构信息

Department of Psychiatry, Trinity College Dublin, St. Patrick's University Hospital, Dublin, Ireland.

Department of Psychology, University College Dublin, Ireland.

出版信息

Alcohol Alcohol. 2019 Jan 9;54(5):551-558. doi: 10.1093/alcalc/agz060.

Abstract

AIM

The aim of this randomized controlled trial was to examine the impact of daily supportive text messages over a 6-month treatment period on mood and alcohol consumption in individuals with a dual diagnosis of alcohol use disorder (AUD) and depression following completion of an inpatient treatment programme.

METHOD

Ninety-five adult participants with AUD and comorbid depression were recruited into this randomized control trial, which took place after completing a 30-day rehabilitation programme. The intervention group (n = 47) received twice-daily supportive text messages over 6-months while control participants (n = 48) had treatment as usual for a 6-month period, with an added 6-month post-treatment follow-up for both groups. Drinking history in the previous 90 days as well as symptoms of depression, anxiety and stress were measured at baseline, 3- and 6-month treatment points and 6-month post treatment follow up.

RESULTS

Depression scores (P = 0.02) and perceived stress scores (P < 0.01) were significantly reduced at 3-month treatment point in the intervention group relative to control participants with small to medium effect. The intervention group also showed a significantly greater reduction in units per drinking day from baseline to 6-month treatment point compared to the control group with a medium effect size (P = 0.03). There were no differences in drinking or mood measures at 6-month post treatment follow-up.

CONCLUSIONS

Supportive text messages provide an early initial benefit in decreasing symptoms of depression and stress, with a further positive impact on alcohol consumption following a longer treatment period. Benefits did not persist six months after the intervention ended.

摘要

目的

本随机对照试验旨在研究在完成 30 天康复计划后,对患有酒精使用障碍(AUD)和抑郁共病的个体在 6 个月治疗期间每天发送支持性短信对情绪和饮酒量的影响。

方法

本随机对照试验共招募了 95 名患有 AUD 和共病抑郁的成年参与者,他们在完成 30 天康复计划后参加了该试验。干预组(n = 47)在 6 个月内每天接受两次支持性短信,而对照组(n = 48)在 6 个月内接受常规治疗,并在两组中增加 6 个月的治疗后随访。在基线、3 个月和 6 个月治疗点以及 6 个月治疗后随访期间,测量了过去 90 天的饮酒史以及抑郁、焦虑和压力症状。

结果

与对照组相比,干预组在 3 个月治疗时的抑郁评分(P = 0.02)和感知压力评分(P < 0.01)显著降低,具有小到中等的效应。与对照组相比,干预组在基线到 6 个月治疗点的每日饮酒量也显著减少,具有中等效应大小(P = 0.03)。在 6 个月治疗后随访时,饮酒和情绪测量均无差异。

结论

支持性短信在减少抑郁和压力症状方面提供了早期的初步益处,在更长的治疗期间对饮酒量有进一步的积极影响。干预结束后 6 个月,益处并未持续。

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