Pallas Health Research and Consultancy B.V., Rotterdam, Netherlands.
European Centre for Disease Prevention and Control, Stockholm, Sweden.
Euro Surveill. 2019 Jul;24(30). doi: 10.2807/1560-7917.ES.2019.24.30.1800614.
BackgroundPeople living with HIV (PLHIV) and people in prison are population groups with a potentially high risk and/or prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection.AimWe conducted a systematic review in order to find prevalence and incidence estimates in these populations in the European Union/European Economic Area (EU/EEA).MethodsOriginal research articles published between January 2005 and February 2017 were retrieved from PubMed and Embase in February 2017.ResultsFifty-two articles were included, providing 97 estimates of HBV/HCV infection prevalence or incidence. Estimates of HBV infection prevalence ranged between 2.9% and43.4% in PLHIV and 0.0% and 25.2% in people in prison. Estimates of HCV infection prevalence ranged from 2.9% to 43.4% in PLHIV and 0.0% to 25.2% in people in prison. Incidence estimates ranged between 0.0 and 2.5 cases per 100 person-years for HBV infection in PLHIV. No such data was available for people in prison. HCV infection incidence ranged between 0.3 and 0.9 cases per 100 person-years in PLHIV and between 1 and 1.2 cases per 100 person-years in people in prison. Prevalence estimates were generally higher than in the general population, especially for HCV infection and among groups with multiple risk factors.ConclusionsPLHIV, people in prison and groups with multiple risk factors, have a high prevalence of HBV and HCV and may be at ongoing risk of infection. These groups should be among the populations prioritised and targeted for active case finding and prevention programmes in the EU/EEA.
艾滋病毒感染者（PLHIV）和囚犯是具有较高乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）感染风险和/或流行率的人群。
我们进行了系统评价，以确定欧盟/欧洲经济区（EU/EEA）中这些人群的流行率和发病率估计值。
于 2017 年 2 月从 PubMed 和 Embase 检索了 2005 年 1 月至 2017 年 2 月期间发表的原始研究文章。
共纳入 52 篇文章，提供了 97 项 HBV/HCV 感染流行率或发病率的估计值。PLHIV 中 HBV 感染流行率的估计值范围为 2.9%至 43.4%，囚犯中为 0.0%至 25.2%。PLHIV 中 HCV 感染流行率的估计值范围为 2.9%至 43.4%，囚犯中为 0.0%至 25.2%。PLHIV 中 HBV 感染的发病率估计值在每 100 人年 0.0 至 2.5 例之间。关于囚犯，没有此类数据。PLHIV 中 HCV 感染的发病率估计值在每 100 人年 0.3 至 0.9 例之间，囚犯中为每 100 人年 1 至 1.2 例。流行率估计值通常高于一般人群，尤其是 HCV 感染和具有多种危险因素的人群。
PLHIV、囚犯和具有多种危险因素的人群 HBV 和 HCV 的流行率较高，并且可能持续存在感染风险。这些人群应是欧盟/欧洲经济区优先和有针对性地开展主动病例发现和预防规划的人群。
