Institute of Technology, University of Tartu, Nooruse 1, Tartu 50411, Estonia.
Sci Signal. 2019 Jul 30;12(592):eaay1167. doi: 10.1126/scisignal.aay1167.
Bacterial persisters survive antibiotic treatment and can cause chronic infections. In this issue of , Pontes and Groisman suggest that there is no specific molecular pathway responsible for persister formation in and that slow growth is the decisive factor.
细菌持久态细胞能够在抗生素治疗中存活下来,并导致慢性感染。在本期的 中,Pontes 和 Groisman 提出,在 中,没有特定的分子途径负责持久态细胞的形成,而缓慢的生长是决定性因素。