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射频膝神经切断术治疗膝关节骨关节炎的适应证:文献综述

Indications of the Neurotomy of Genicular Nerves by Radiofrequency for the Treatment of Knee Osteoarthritis: A Literature Review.

作者信息

Ariel de Lima Diego, Gonçalves Marcelo Carvalho Krause, Grando Souterland Thiago Correia E Sá, Cintra Thiago Luiz de Lima, Pinto Dilamar Moreira, Gonçalves Romeu Krause

机构信息

Grupo de Joelho do Instituto de Traumatologia e Ortopedia Romeu Krause (ITORK), Recife, PE, Brasil.

Universidade Federal Rural do Semi-Árido (UFERSA), Mossoró, RN, Brasil.

出版信息

Rev Bras Ortop (Sao Paulo). 2019 May;54(3):233-240. doi: 10.1055/s-0039-1692121. Epub 2019 Jun 27.

DOI:10.1055/s-0039-1692121
PMID:31363275
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6597460/
Abstract

Osteoarthritis (OA) is one of the most frequent and incapacitating pathologies today, especially of the knee. Among the possible approaches for knee OA, the neurotomy of the genicular nerves by radiofrequency (RF) has been gaining prominence. However, as this is a relatively new procedure, indications for its implementation are still unclear. The objective of the present review is to identify the main indications of the use of RF for the treatment of knee OA in the medical literature. A review of the literature was performed in January 2018 through a search in the PubMed, ClinicalKey and Google Scholar databases. After reviewing the main articles on the subject, it was concluded that the main indications of the use of RF for the treatment of knee OA were: OA Kellgren-Lawrence grades 3 and 4, with moderate to severe pain and failure of conservative treatment, mainly in elderly people; persistence of pain even after total knee arthroplasty (TKA); patients with an indication for TKA who refuse to undergo surgical treatment.

摘要

骨关节炎(OA)是当今最常见且使人丧失活动能力的病症之一,尤其是膝关节骨关节炎。在膝关节OA的可能治疗方法中,通过射频(RF)进行膝神经切断术越来越受到关注。然而,由于这是一种相对较新的手术,其实施指征仍不明确。本综述的目的是在医学文献中确定使用RF治疗膝关节OA的主要指征。2018年1月通过在PubMed、ClinicalKey和谷歌学术数据库中进行检索,对文献进行了综述。在查阅了关于该主题的主要文章后,得出结论:使用RF治疗膝关节OA的主要指征为:Kellgren-Lawrence 3级和4级OA,伴有中度至重度疼痛且保守治疗无效,主要见于老年人;全膝关节置换术(TKA)后仍持续疼痛;有TKA指征但拒绝接受手术治疗的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65cb/6597460/1dd7973c7ac5/10-1055-s-0039-1692121-i180037pt-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65cb/6597460/f0d9b4ec9c11/10-1055-s-0039-1692121-i180037en-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65cb/6597460/1dd7973c7ac5/10-1055-s-0039-1692121-i180037pt-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65cb/6597460/f0d9b4ec9c11/10-1055-s-0039-1692121-i180037en-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65cb/6597460/1dd7973c7ac5/10-1055-s-0039-1692121-i180037pt-1.jpg

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本文引用的文献

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Study protocol for a randomised controlled trial of ultrasound-guided pulsed radiofrequency of the genicular nerves in the treatment of patients with osteoarthritis knee pain.一项随机对照试验研究方案,探讨超声引导下关节内神经射频脉冲治疗膝骨关节炎疼痛的效果。
BMJ Open. 2017 Nov 3;7(11):e016377. doi: 10.1136/bmjopen-2017-016377.
2
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis.前瞻性、多中心、随机、交叉临床试验比较了冷却射频消融与皮质类固醇注射治疗骨关节炎膝关节疼痛的安全性和有效性。
Reg Anesth Pain Med. 2018 Jan;43(1):84-91. doi: 10.1097/AAP.0000000000000690.
3
Cooled Radiofrequency Ablation of the Genicular Nerves for Chronic Pain due to Knee Osteoarthritis: Six-Month Outcomes.
膝关节骨性关节炎慢性疼痛的神经冷却射频消融:6 个月的结果。
Pain Med. 2017 Sep 1;18(9):1631-1641. doi: 10.1093/pm/pnx069.
4
A Review of Long-Term Pain Relief after Genicular Nerve Radiofrequency Ablation in Chronic Knee Osteoarthritis.膝状神经射频消融术治疗慢性膝骨关节炎后的长期疼痛缓解情况综述
Pain Physician. 2017 Mar;20(3):E437-E444.
5
Bipolar Versus Unipolar Intraarticular Pulsed Radiofrequency Thermocoagulation in Chronic Knee Pain Treatment: A Prospective Randomized Trial.双相与单相关节内脉冲射频热凝术治疗慢性膝关节疼痛的前瞻性随机试验
Pain Physician. 2017 Mar;20(3):197-206.
6
The genicular nerve: radiofrequency lesion application for chronic knee pain.膝关节神经:射频损伤在慢性膝关节疼痛中的应用。
Turk J Med Sci. 2017 Feb 27;47(1):268-272. doi: 10.3906/sag-1601-171.
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Clinical settings in knee osteoarthritis: Pathophysiology guides treatment.膝关节骨关节炎的临床情况:病理生理学指导治疗。
Maturitas. 2017 Feb;96:54-57. doi: 10.1016/j.maturitas.2016.11.013. Epub 2016 Nov 20.
8
Analgesic Effect and Functional Improvement Caused by Radiofrequency Treatment of Genicular Nerves in Patients With Advanced Osteoarthritis of the Knee Until 1 Year Following Treatment.膝关节晚期骨关节炎患者经射频治疗膝神经后直至治疗后1年的镇痛效果及功能改善情况
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Int J Rheum Dis. 2018 Oct;21(10):1772-1778. doi: 10.1111/1756-185X.12925. Epub 2016 Aug 12.