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在中年墨西哥女性中,身高与自我报告的糖尿病呈负相关。

Stature is inversely associated with self-reported diabetes in middle-aged Mexican women.

作者信息

Puchner Karl P, Lopez-Ridaura Ruy, Ortiz-Panozo Eduardo, Vieitez Isabel, Lajous Martín

机构信息

Center for Population Health Research National Institute of Public Health CuernavacaMorelos Mexico Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.

出版信息

Rev Panam Salud Publica. 2017 Mar 6;41:e32. doi: 10.26633/RPSP.2017.32. eCollection 2017.

Abstract

OBJECTIVE

To investigate whether stature is associated with two highly prevalent cardiom- etabolic disorders-diabetes mellitus (DM) and high blood pressure (HBP) -in middle-aged Mexican women.

METHODS

ESMaestras

RESULTS

After adjusting for birth cohort, ethnicity, family history, birthweight, occupation of household's head during participant's childhood, menopausal status, and geographical region of birthplace, stature was inversely associated with DM, with the odds for DM being 9% higher in the lowest stature quintile when compared to the highest stature quintile. Stratification for location of residence resulted in confirmation of the above-mentioned findings only in partici- pants living in urban environments.

CONCLUSIONS

We found an inverse association of stature with DM but not with HBP. Our data suggest that urban setting might be an important effect modifier of this association, which merits further investigation since it might provide valuable insights into the epidemiological transition occurring in developing countries.

摘要

目的

研究身材是否与中年墨西哥女性中两种高度常见的心脏代谢疾病——糖尿病(DM)和高血压(HBP)相关。

方法

ESMaestras

结果

在对出生队列、种族、家族病史、出生体重、参与者童年时期户主的职业、绝经状态和出生地的地理区域进行调整后,身材与糖尿病呈负相关,与最高身材五分位数相比,最低身材五分位数患糖尿病的几率高9%。按居住地点分层后,仅在居住在城市环境中的参与者中证实了上述发现。

结论

我们发现身材与糖尿病呈负相关,但与高血压无关。我们的数据表明,城市环境可能是这种关联的一个重要效应修饰因素,值得进一步研究,因为它可能为发展中国家正在发生的流行病学转变提供有价值的见解。

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Genetically determined height and coronary artery disease.基因决定的身高与冠状动脉疾病。
N Engl J Med. 2015 Apr 23;372(17):1608-18. doi: 10.1056/NEJMoa1404881. Epub 2015 Apr 8.

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