用去甲丙咪嗪治疗滥用可卡因的美沙酮维持治疗患者。
Treating cocaine abusing methadone maintenance patients with desipramine.
作者信息
Kosten T, Gawin F, Schumann B
机构信息
Substance Abuse Treatment Unit, Connecticut Mental Health Center.
出版信息
NIDA Res Monogr. 1988;81:237-41.
PMID:3136366
Abstract
Intravenous cocaine use in methadone patients has become a major problem because of both the complications of cocaine use and the potential spread of AIDS. During an eight week open trial we found that desipramine reduced cocaine craving and use in eight cocaine abusing methadone maintenance patients compared to eight patients getting no medication execept methadone.
摘要
美沙酮治疗患者静脉注射可卡因已成为一个主要问题，这是由于使用可卡因会带来并发症以及艾滋病可能传播。在一项为期八周的开放试验中，我们发现，与八名仅接受美沙酮治疗而未服用其他药物的患者相比，地昔帕明减少了八名滥用可卡因的美沙酮维持治疗患者对可卡因的渴望及使用量。
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