Kosten T R, Schumann B, Wright D, Carney M K, Gawin F H
Substance Abuse Treatment Unit, Connecticut Mental Health Center, New Haven, CT.
J Clin Psychiatry. 1987 Nov;48(11):442-4.
Intravenous cocaine use is a major problem in methadone maintenance programs. In this pilot study of 16 cocaine-abusing methadone maintenance patients, 8 received desipramine and 8 received no medication other than methadone. During an 8-week open trial the desipramine patients reported significantly less cocaine craving and had less cocaine use than the other patients.