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A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients.

作者信息

Kosten T R, Schumann B, Wright D, Carney M K, Gawin F H

机构信息

Substance Abuse Treatment Unit, Connecticut Mental Health Center, New Haven, CT.

出版信息

J Clin Psychiatry. 1987 Nov;48(11):442-4.

PMID:3680185
Abstract

Intravenous cocaine use is a major problem in methadone maintenance programs. In this pilot study of 16 cocaine-abusing methadone maintenance patients, 8 received desipramine and 8 received no medication other than methadone. During an 8-week open trial the desipramine patients reported significantly less cocaine craving and had less cocaine use than the other patients.

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