Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
Chem Commun (Camb). 2019 Aug 13;55(66):9833-9836. doi: 10.1039/c9cc03537k.
Herein, through using electropolymerized pyrrole (PPy) to coat near-infrared upconversion nanoparticles (UCNPs) on an indium tin oxide (ITO) electrode, the as-prepared PPy/UCNPs photoelectrode could generate an interfacial electric field, release rare earth ions and induce reactive oxygen species (ROS) in PC12 cells under NIR irradiation, which could realize wireless neurite development and outgrowth.
在此，通过在氧化铟锡（ITO）电极上用电聚合吡咯（PPy）包覆上转换纳米粒子（UCNPs），制备的 PPy/UCNPs 光电极在近红外光照射下可产生界面电场，释放稀土离子并诱导 PC12 细胞中活性氧物质（ROS）的产生，从而实现无线的神经突生长和延伸。
