Allouch P, Denis C, Ghnassia J C, Sire O
Service Microbiologie, Centre Hospitalier de Versailles, Hôpital André Mignot, Le Chesnay.
Pathol Biol (Paris). 1988 May;36(5):465-71.
1,707 non replicate clinical strains of Pseudomonas aeruginosa from non teaching hospitals were investigated. Beta-lactam antibiotics were tested by agar disk diffusion method. Variance analysis revealed a significant interaction between strains and experimental laboratories. The bacterial population was grouped according to the diameters of inhibition zones of antibiogram, into five phenotypes. Pseudomonas aeruginosa is frequently isolated from urines and pulmonary sampling, rarely from blood cultures. Resistance to beta-lactams increased significantly with the duration of hospitalisation, and age of patients. Clinical strains are significantly more resistant in blood cultures, and for strains isolated from reanimation. 84% of strains are susceptible to ticarcillin.
对来自非教学医院的1707株非重复铜绿假单胞菌临床菌株进行了研究。采用琼脂纸片扩散法检测β-内酰胺类抗生素。方差分析显示菌株与实验实验室之间存在显著交互作用。根据抗菌谱抑菌圈直径将细菌群体分为五种表型。铜绿假单胞菌常从尿液和肺部样本中分离得到，很少从血培养中分离得到。对β-内酰胺类抗生素的耐药性随住院时间和患者年龄的增加而显著增加。临床菌株在血培养中以及从复苏患者中分离得到的菌株耐药性显著更高。84%的菌株对替卡西林敏感。
