Chan I Ping, Weng Min Chieh, Hsueh Tung, Lin Yun Chang, Lin Shiun Long
Veterinary Medical Teaching Hospital, National Chung Hsing University, Taichung 40227, Taiwan.
Department of Veterinary Medicine, National Chung Hsing University, Taichung 40227, Taiwan.
J Vet Sci. 2019 Jul;20(4):e34. doi: 10.4142/jvs.2019.20.e34.
The right pulmonary artery distensibility (RPAD) index has been used in dogs with pulmonary hypertension (PH) caused by heartworm infection, myxomatous mitral valve disease, or patent ductus arteriosus. We hypothesized that this index correlates with the tricuspid regurgitation pressure gradient (TRPG) assessed by echocardiography and could predict survival in dogs with PH secondary to various causes. To assess this hypothesis, the medical records of 200 client-owned dogs at a referral institution were retrospectively reviewed. The RPAD index and the ratios of acceleration time to peak pulmonary artery flow (AT) and to the ejection time of pulmonary artery flow (ET) were recorded for each dog. The owners were contacted for follow-up assessments. The findings indicated that the RPAD index was correlated with the TRPG (R² = 0. 362, < 0.001). The survival time was significantly shorter in dogs with an RPAD index ≤ 21% that were followed up for 3 months and in dogs with an RPAD index ≤ 24% that were followed up for 1 year. Thus, the RPAD index was correlated with the TRPG and could predict the clinical outcome in dogs with PH caused by various diseases. This index could be used to evaluate the severity of PH in dogs without tricuspid regurgitation.
右肺动脉扩张性（RPAD）指数已用于患有由心丝虫感染、黏液瘤性二尖瓣疾病或动脉导管未闭引起的肺动脉高压（PH）的犬类。我们假设该指数与通过超声心动图评估的三尖瓣反流压力梯度（TRPG）相关，并且可以预测继发于各种原因的PH犬的生存情况。为了评估这一假设，我们回顾性地查阅了一家转诊机构的200只客户拥有犬的病历。记录每只犬的RPAD指数以及加速时间与肺动脉血流峰值（AT）和肺动脉血流射血时间（ET）的比值。与犬主联系以进行随访评估。结果表明，RPAD指数与TRPG相关（R² = 0.362，<0.001）。随访3个月的RPAD指数≤21%的犬和随访1年的RPAD指数≤24%的犬的生存时间明显更短。因此，RPAD指数与TRPG相关，并且可以预测由各种疾病引起的PH犬的临床结局。该指数可用于评估无三尖瓣反流的犬的PH严重程度。
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