Department of Neurology and Neurorehabilitation, IRCCS Mondino Foundation, Pavia, Italy.
Université de Paris, INSERM UMR 1266 IMA-BRAIN, Department of Neuroradiology, Centre Hospitalier Sainte Anne, Paris, France.
Ann Neurol. 2019 Oct;86(4):480-492. doi: 10.1002/ana.25563. Epub 2019 Aug 24.
Significant hematoma expansion (HE) affects one-fifth of people within 24 hours after acute intracerebral hemorrhage (ICH), and its prevention is an appealing treatment target. Although the computed tomography (CT)-angiography spot sign predicts HE, only a minority of ICH patients receive contrast injection. Conversely, noncontrast CT (NCCT) is used to diagnose nearly all ICH, so NCCT markers represent a widely available alternative for prediction of HE. However, different NCCT signs describe similar features, with lack of consensus on the optimal image acquisition protocol, assessment, terminology, and diagnostic criteria. In this review, we propose practical guidelines for detecting, interpreting, and reporting NCCT predictors of HE. ANN NEUROL 2019;86:480-492.
血肿扩大(HE)在急性脑出血(ICH)后 24 小时内影响五分之一的人,预防血肿扩大是一个有吸引力的治疗目标。虽然 CT 血管造影点征可预测 HE,但只有少数 ICH 患者接受造影剂注射。相反,非对比 CT(NCCT)用于诊断几乎所有 ICH,因此 NCCT 标志物是预测 HE 的广泛可用替代方法。然而,不同的 NCCT 征象描述了相似的特征,缺乏关于最佳图像采集方案、评估、术语和诊断标准的共识。在这篇综述中,我们提出了检测、解释和报告 NCCT 预测 HE 的实用指南。ANN NEUROL 2019;86:480-492.