Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Chem Commun (Camb). 2019 Aug 15;55(67):9959-9962. doi: 10.1039/c9cc04660g.
On the basis of BSA stabilized tetraphenylethylene nanocrystals (BSA-TPE NCs) as aggregation-induced enhanced electrochemiluminescence (ECL) emitters with high ECL efficiency and good biocompatibility, as well as molecular recognition between β-CD and ferrocene, an ultrasensitive and versatile ECL biosensing platform was constructed to achieve microRNA detection in cancer cells.
基于 BSA 稳定的四苯乙烯纳米晶体(BSA-TPE NCs)作为具有高 ECL 效率和良好生物相容性的聚集诱导增强电化学发光(ECL)发射器,以及β-CD 与二茂铁之间的分子识别,构建了一种超灵敏且多功能的 ECL 生物传感平台,用于实现癌细胞中 microRNA 的检测。