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载抗生素陶瓷胸骨用于一名患有深部胸骨伤口感染患者的胸骨置换。

Antibiotic-loaded ceramic sternum for sternal replacement in a patient with deep sternal wound infection.

作者信息

Tricard Jeremy, Chermat Anaëlle, Denes Eric, Bertin François

机构信息

Thoracic and Cardiovascular Surgery Department, Limoges teaching Hospital, Limoges, France.

R&D Department, I.Ceram, Limoges, France.

出版信息

Interact Cardiovasc Thorac Surg. 2019 Dec 1;29(6):973-975. doi: 10.1093/icvts/ivz182.

DOI:10.1093/icvts/ivz182
PMID:31365090
Abstract

A 68-year-old man presented with destruction of his sternum after cardiac surgery. Classical management with multiple debridements, vacuum dressings and antibiotics failed. A replacement of his sternum was performed using an antibiotic-loaded porous alumina ceramic sternum. Despite the infected wound, the ceramic sternum did not get infected due to the high antibiotic concentration obtained locally. Two years after the surgery, no relapse occurred and the pulmonary function tests improved.

摘要

一名68岁男性在心脏手术后出现胸骨破坏。采用多次清创、负压敷料和抗生素的传统治疗方法失败。使用载有抗生素的多孔氧化铝陶瓷胸骨对其进行了胸骨置换。尽管伤口感染,但由于局部获得高浓度抗生素,陶瓷胸骨未被感染。手术后两年,未出现复发,肺功能测试结果有所改善。

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