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心脏手术后胸骨深部伤口感染患者使用载抗生素骨水泥。

Using antibiotic-loaded bone cement for a patient with deep sternal wound infection after cardiac surgery.

机构信息

Department of Cardiovascular Surgery, Wuxi People's Hospital/Wuxi Affiliated Hospital of Nanjing Medical University, Wuxi, China.

出版信息

Interact Cardiovasc Thorac Surg. 2022 Jun 1;34(6):1150-1151. doi: 10.1093/icvts/ivab332.

DOI:10.1093/icvts/ivab332
PMID:34849902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9159415/
Abstract

A 67-year-old male presented with sternal dehiscence following open cardiac surgery. Extensive debridement and attempted closure failed, and the wound had since been managed with vacuum-assisted closure therapy, with little progress. We treated him with antibiotic-loaded bone cement to repair the wound defect. After 3 weeks, the wound healed with excellent result. To our knowledge, this is the first report of antibiotic-loaded bone cement for deep sternal wound infection.

摘要

一位 67 岁男性在接受心脏直视手术后出现胸骨裂开。广泛清创和尝试关闭失败，此后该伤口一直采用真空辅助闭合治疗，但进展甚微。我们使用载抗生素骨水泥治疗他的伤口缺陷。3 周后，伤口愈合良好。据我们所知，这是首例使用载抗生素骨水泥治疗深部胸骨伤口感染的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f74/9159415/a3ffa5ca0c14/ivab332f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f74/9159415/a3ffa5ca0c14/ivab332f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f74/9159415/a3ffa5ca0c14/ivab332f1.jpg

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引用本文的文献

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The combined application of antibiotic-loaded bone cement and vacuum sealing drainage for sternal reconstruction in the treatment of deep sternal wound infection.抗生素骨水泥联合真空封闭引流在治疗胸骨深部感染中的应用
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本文引用的文献

1
Deep Sternal Wound Infection: Diagnosis, Treatment and Prevention.胸骨深部伤口感染：诊断、治疗与预防。
J Cardiothorac Vasc Anesth. 2020 Jun;34(6):1602-1613. doi: 10.1053/j.jvca.2019.09.019. Epub 2019 Sep 18.
2
Sternal reconstruction after post-sternotomy mediastinitis.胸骨切开术后纵隔炎后的胸骨重建。
J Cardiothorac Surg. 2017 Nov 2;12(1):94. doi: 10.1186/s13019-017-0656-7.
3
Antibiotic-loaded cement in orthopedic surgery: a review.骨科手术中载抗生素骨水泥：综述
ISRN Orthop. 2011 Aug 7;2011:290851. doi: 10.5402/2011/290851. eCollection 2011.
4
Two-stage arthroplasty for prosthetic joint infection: a systematic review of acute kidney injury, systemic toxicity and infection control.二期关节成形术治疗人工关节感染：急性肾损伤、全身毒性和感染控制的系统评价。
J Arthroplasty. 2013 Oct;28(9):1490-8.e1. doi: 10.1016/j.arth.2013.02.035. Epub 2013 Apr 8.
5
Polymethylmethacrylate: properties and contemporary uses in orthopaedics.聚甲基丙烯酸甲酯：性质及在矫形外科中的当代用途。
J Am Acad Orthop Surg. 2010 May;18(5):297-305. doi: 10.5435/00124635-201005000-00006.