死后血液、玻璃体液和滑液中的尿素、尿酸和肌酐：一项比较与相关性研究。
Urea, Uric Acid, and Creatinine in Postmortem Blood, Vitreous Humor, and Synovial Fluid: A Comparative and Correlation Study.
作者信息
Srettabunjong Supawon, Thongphap Wantawanop, Chittamma Anchalee
机构信息
Department of Forensic Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Division of Clinical Chemistry, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
出版信息
J Forensic Sci. 2020 Jan;65(1):128-133. doi: 10.1111/1556-4029.14138. Epub 2019 Jul 31.
Urea, uric acid, and creatinine have been demonstrated to be relatively stable in postmortem blood (BL), thus being useful for diagnostic purposes. However, no studies have explored their levels in BL, vitreous humor (VH), and synovial fluid (SF) concurrently. Therefore, we measured and compared their levels in these fluids. We also determined the effects of various factors on their levels. The results indicated that BL urea, uric acid, and creatinine levels were significantly higher than VH and SF levels. VH and SF urea levels and SF creatinine levels had a strong correlation with BL urea and creatinine levels, respectively. BL creatinine levels were higher in men than in women. BL and SF creatinine levels were negatively correlated with age. SF uric acid and BL, VH, and SF creatinine levels exhibited a positive correlation with weight. Only VH creatinine levels were positively correlated with body mass index. None of urea, uric acid, and creatinine levels were correlated with postmortem interval.
尿素、尿酸和肌酐已被证明在死后血液（BL）中相对稳定，因此可用于诊断目的。然而，尚无研究同时探讨它们在血液、玻璃体液（VH）和滑液（SF）中的水平。因此，我们测量并比较了这些液体中它们的水平。我们还确定了各种因素对它们水平的影响。结果表明，血液中的尿素、尿酸和肌酐水平显著高于玻璃体液和滑液水平。玻璃体液和滑液中的尿素水平以及滑液中的肌酐水平分别与血液中的尿素和肌酐水平密切相关。男性血液中的肌酐水平高于女性。血液和滑液中的肌酐水平与年龄呈负相关。滑液中的尿酸以及血液、玻璃体液和滑液中的肌酐水平与体重呈正相关。只有玻璃体液中的肌酐水平与体重指数呈正相关。尿素、尿酸和肌酐水平均与死后间隔时间无关。
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