Trabzon Ahi Evren Gogus Kalp Ve Damar Cerrahisi Egitim Ve Arastirma Hastanesi - Cardiology, Trabzon - Turkey.
Trabzon Kanuni Egitim Ve Arastirma Hastanesi - Endocrinology, Trabzon - Turkey.
Arq Bras Cardiol. 2019 Jul 29;113(2):207-215. doi: 10.5935/abc.20190134.
Myocardial performance index (MPI), demonstrates both systolic and diastolic functions of the left ventricle. Presystolic wave (PSW) is frequently detected on Doppler examination of the left ventricular outflow tract and possible mechanism of PSW is impaired LV compliance and left ventricular stiffness.
To investigate the relationship between PSW and MPI in type 2 diabetic patients.
A total of 129 type 2 diabetic patients were included in this study. Patients were divided into two groups according to the presence of PSW on Doppler echocardiography. There were 90 patients (38 male, mean age 57.77 ± 10.91 years) in the PSW-positive group and 39 patients (13 male; mean age: 55.31 ± 11.29 years) in the PSW-negative group. The p values of < 0.05 were considered statistically significant.
MPI was higher in PSW- positive group (0.63 ± 0.17vs 0.52 ± 0.13, p < 0.001). In addition, subclinical left ventricle dysfunction (LVD) was higher in the PSW- positive group (p = 0.029). Univariate analysis showed that the presence of PSW associated with abnormal MPI (p = 0.031). Pearson correlation analysis showed that PSW velocity correlated with MPI (r: 0.286, p = 0.006).
Presence of the PSW on Doppler examination was associated with subclinical LV dysfunction in patients with DM type 2. This easy-to-perform echocardiographic parameter may be related to subclinical LVD among patients with type 2 DM.
心肌做功指数（MPI）可同时评估左心室的收缩和舒张功能。左心室流出道多普勒检查常可检测到收缩前期波（PSW），其可能的发生机制为左心室顺应性下降和僵硬度增加。
探讨 2 型糖尿病患者 PSW 与 MPI 的关系。
本研究共纳入 129 例 2 型糖尿病患者。根据多普勒超声心动图是否存在 PSW 将患者分为两组。PSW 阳性组 90 例（男 38 例，平均年龄 57.77 ± 10.91 岁），PSW 阴性组 39 例（男 13 例，平均年龄 55.31 ± 11.29 岁）。P 值＜0.05 为差异有统计学意义。
PSW 阳性组的 MPI 较高（0.63 ± 0.17 比 0.52 ± 0.13，P ＜0.001）。此外，PSW 阳性组亚临床左心室功能障碍（LVD）的发生率较高（P = 0.029）。单因素分析显示 PSW 的存在与异常 MPI 相关（P = 0.031）。Pearson 相关分析显示 PSW 速度与 MPI 相关（r：0.286，P = 0.006）。
多普勒超声心动图检查中 PSW 的存在与 2 型糖尿病患者亚临床 LV 功能障碍有关。这种易于实施的超声心动图参数可能与 2 型糖尿病患者的亚临床 LVD 有关。
