甲真菌病中的指甲修剪及其与正常指甲和甲银屑病的比较。
Nail clipping in onychomycosis and comparison with normal nails and ungual psoriasis.
作者信息
Trevisan Flávia, Werner Betina, Pinheiro Rosangela Lameira
机构信息
Department of Dermatology, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba (PR), Brazil.
Department of Pathology, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba (PR), Brazil.
出版信息
An Bras Dermatol. 2019 Jul 29;94(3):344-347. doi: 10.1590/abd1806-4841.20198301.
BACKGROUND
Of all nail disorders seen in dermatology offices, half of them are due to onychomycosis. The main differential diagnosis is nail psoriasis. The objective of this study was to compare the microscopic findings, other than the presence of fungi, in the clipping of onychomycosis versus normal nails and nail psoriasis.
METHODS
Cross-sectional study of onychomycosis cases, analyzed by clipping and compared with data on normal nails and those with nail psoriasis.
RESULTS
Sixty-two onychomycosis samples were compared with 30 normal nails and 50 nails with psoriasis. In onychomycosis, measurement of subungual region, serous lakes, neutrophils and number of layers of parakeratosis are more intense than in psoriasis. Onychocariosis is less common in psoriasis, while bacteria are more frequent. The nail transition zone is more commonly blurred and irregular in onychomycosis.
CONCLUSION
Clipping helps in the differential diagnosis of onychomycosis and nail psoriasis and may be useful even when fungi are not found.
背景
在皮肤科诊所所见的所有指甲疾病中，其中一半是由甲癣引起的。主要鉴别诊断是指甲银屑病。本研究的目的是比较甲癣、正常指甲和指甲银屑病的指甲剪切片中除真菌存在之外的微观发现。
方法
对甲癣病例进行横断面研究，通过剪切片进行分析，并与正常指甲和指甲银屑病的数据进行比较。
结果
将62份甲癣样本与30份正常指甲和50份银屑病指甲进行比较。在甲癣中，指甲下区域、浆液湖、中性粒细胞的测量以及不全角化层数比银屑病中更明显。甲下甲癣在银屑病中较少见，而细菌更常见。甲癣中指甲过渡区更常模糊且不规则。
结论
剪切片有助于甲癣和指甲银屑病的鉴别诊断，即使未发现真菌也可能有用。
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