Yuan M J, Li S H, Huang Y, Fu W D
Department of Infectious Diseases, the First People's Hospital in Yueyang, Yueyang 414000, China.
Department of Rehabilitation, the First People's Hospital in Yueyang, Yueyang 414000, China.
Zhonghua Nei Ke Za Zhi. 2019 Aug 1;58(8):596-598. doi: 10.3760/cma.j.issn.0578-1426.2019.08.009.
To explore how to diagnose and treat brucellosis accurately and timely in patients with fever of unkown origin in non-pastoral areas. The epidemiological history, clinical symptoms, complete blood counts, procalcitonin and treatment efficacy of 7 patients with brucellosis were analyzed retrospectively. Some characteristic manifestations should be differentiated from tuberculosis. The clinical symptoms were relieved after combination of doxycycline, rifampicin, levofloxacin and amikacin for 6 weeks, only one patient with bone destruction needed orthopedic surgery. The overall response rate was 6/7. No relapse occurred during half year follow-up.
探讨非牧区不明原因发热患者布氏杆菌病的准确及时诊断及治疗方法。回顾性分析7例布氏杆菌病患者的流行病学史、临床症状、血常规、降钙素原及治疗效果。需与结核病鉴别一些特征性表现。采用多西环素、利福平、左氧氟沙星及阿米卡星联合治疗6周后临床症状缓解,仅1例有骨质破坏患者需行骨科手术。总有效率为6/7。半年随访期间无复发。