Department of Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany
Institute of Neuropathology, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Anticancer Res. 2019 Aug;39(8):3991-4002. doi: 10.21873/anticanres.13554.
Different phenomena can result in enlargement of mental foramen and mandibular canal. At the foreground of diagnosis is the assessment of the biological properties of the tissue which causes such detailed lesions of the skeleton.
This report describes a palpable mass at the site of the mental foramen with radiological evidence of an extensive enlargement of the bony portion of the inferior alveolar nerve. These findings were the reason for surgical exploration. Surprisingly, the mass was inflammatory tissue that had proliferated in the canal and foramina. The lesion had grown around the nerve and did not infiltrate it. The diagnosis of lymphatic hyperplasia was made. Other potential causes of the unusual radiological and clinical findings are explained with reference to the literature.
Imaging does not provide a safe assessment of tumor biology. Surgical exploration with detailed tissue examination of the tumor provides the basis for appropriate therapy.
不同的现象可能导致颏孔和下颌管扩大。诊断的重点是评估引起骨骼这种详细病变的组织的生物学特性。
本报告描述了颏孔部位可触及的肿块,影像学证据显示下颌神经骨段广泛扩大。这些发现是进行手术探查的原因。令人惊讶的是,肿块是在管内和孔内增殖的炎症组织。病变已围绕神经生长,并未浸润神经。诊断为淋巴组织增生。参考文献解释了其他可能导致这种不寻常的影像学和临床表现的潜在原因。
影像学检查不能对肿瘤生物学进行安全评估。手术探查并对肿瘤进行详细的组织检查为制定适当的治疗方案提供了依据。