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与B细胞淋巴瘤相关的下牙槽神经管扩大及颏神经病变:一例报告及文献综述

Enlargement of Inferior Alveolar Nerve Canal and Mental Neuropathy Associated With B-Cell Lymphoma: A Case Report and Literature Review.

作者信息

De La Guerra José Antonio, Kufta Kenneth, Shanti Rabie, Panchal Neeraj

机构信息

Resident in Oral and Maxillofacial Surgery, Cook County Health and Hospital System, John H. Stroger Jr. Hospital of Cook County, Chicago, IL.

Resident in Oral and Maxillofacial Surgery, University of Pennsylvania Health System, Perelman Center for Advanced Medicine South Pavilion, Philadelphia, PA.

出版信息

J Oral Maxillofac Surg. 2022 Sep;80(9):1534-1543. doi: 10.1016/j.joms.2022.04.006. Epub 2022 Apr 15.

Abstract

Enlargement of an inferior alveolar nerve canal (IANC) on radiographic imaging can indicate the presence of a wide variety of pathologic entities. Oral and maxillofacial surgeons have the unique opportunity to regularly examine panoramic radiographs and must exercise proficient clinical judgment when noting abnormal findings on imaging. While malignant processes associated with IANC enlargement are uncommon, these pathologies do occur and may be associated with significant sequelae, especially when accompanied by a delay in diagnosis and in treatment. The purpose of this case report is to describe a case in which a patient presented with mental nerve neuropathy associated with unilateral IANC enlargement on radiography, which was found to be a B-cell lymphoma on biopsy. More importantly, we aim to remind oral and maxillofacial surgeons of this rare presentation of a malignant process so as to promote prompt recognition and referral for appropriate treatment.

摘要

影像学检查显示下牙槽神经管(IANC)扩大可能提示多种病理情况的存在。口腔颌面外科医生有机会定期查看全景X线片,在影像学检查发现异常时必须具备熟练的临床判断力。虽然与IANC扩大相关的恶性病变并不常见,但这些病理情况确实会发生,且可能伴有严重后果,尤其是在诊断和治疗延迟的情况下。本病例报告的目的是描述一例患者,其在影像学检查中表现为与单侧IANC扩大相关的颏神经病变,活检发现为B细胞淋巴瘤。更重要的是,我们旨在提醒口腔颌面外科医生注意这种罕见的恶性病变表现,以促进及时识别并转诊至合适的治疗机构。

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