肝胆期高信号强度磁共振成像预测肝细胞癌患者的长期生存。
High-signal-intensity MR Image in the Hepatobiliary Phase Predicts Long-term Survival in Patients With Hepatocellular Carcinoma.
机构信息
Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan.
Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
出版信息
Anticancer Res. 2019 Aug;39(8):4219-4225. doi: 10.21873/anticanres.13583.
BACKGROUND/AIM: The aim of the study was to evaluate surgical outcomes of patients with high-signal intensity (SI) image hepatocellular carcinoma (HCC).
PATIENTS AND METHODS
Between 2008 and 2013, 257 HCC patients were retrospectively evaluated. A total of 21 patients were diagnosed as high-SI image HCC, 215 as low-SI image HCC, and 21 patients as mixed (high and low)-SI image HCC in the hepatobiliary (HB) phase of MRI. Five-year overall survival (OS) and recurrence-free survival (RFS) were compared among patient groups.
RESULTS
The 5-year OS and RFS rates were significantly higher in patients with high-SI image HCC (100% and 56%) than in patients with low-SI image HCC (71%; p=0.097 and 38%; p=0.0209) and in patients with mixed-SI image HCC (73%; p=0.0329 and 9%; p=0.0021). High-SI image was an independent prognostic factor for OS (relative risk 0.167, p=0.0178) and RFS (relative risk 0.471, p=0.0322) on multivariate analysis.
CONCLUSION
Patients with high-SI image HCC showed favorable long-term survival after curative surgery.
背景/目的：本研究旨在评估高信号强度（SI）图像肝细胞癌（HCC）患者的手术治疗效果。
方法
回顾性分析 2008 年至 2013 年间 257 例 HCC 患者。MRI 肝胆期检查中，21 例患者被诊断为高 SI 图像 HCC，215 例为低 SI 图像 HCC，21 例为混合（高和低）SI 图像 HCC。比较各组患者的 5 年总生存率（OS）和无复发生存率（RFS）。
结果
高 SI 图像 HCC 患者的 5 年 OS 和 RFS 率明显高于低 SI 图像 HCC 患者（100%和 56%，p=0.097 和 38%，p=0.0209）和混合 SI 图像 HCC 患者（73%，p=0.0329 和 9%，p=0.0021）。高 SI 图像是 OS（相对风险 0.167，p=0.0178）和 RFS（相对风险 0.471，p=0.0322）的独立预后因素。
结论
根治性手术后，高 SI 图像 HCC 患者的长期生存状况良好。
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