Mullath Anju, Krishna Murali
Department of Gastroenterology, Lakeshore Hospital and Research Centre, Kochi 682040, Kerala, India.
Department of Surgery, Military Hospital, Palampur 176061, Himachal Pradesh, India.
World J Gastrointest Surg. 2019 Jun 27;11(6):287-295. doi: 10.4240/wjgs.v11.i6.287.
Hepatocellular carcinoma is one of the leading malignancies worldwide. Early detection of hepatocellular carcinoma and its management in the form of liver transplantation offers an attractive treatment option. The Milan criteria, proposed by Mazzaferro et al, have been the standard for selecting patients with hepatocellular carcinoma for transplantation. Recently, several studies have shown that even patients selected outside the Milan criteria can undergo transplantation with a relatively good outcome. This article examines the currently existing criteria other than the Milan criteria and also evaluates use of alpha-fetoprotein and positron emission tomography scans to predict the chance of recurrence.
肝细胞癌是全球主要的恶性肿瘤之一。早期检测肝细胞癌并通过肝移植进行治疗是一种有吸引力的治疗选择。Mazzaferro等人提出的米兰标准一直是选择肝细胞癌患者进行移植的标准。最近，多项研究表明，即使是不符合米兰标准的患者也可以接受移植，且预后相对较好。本文探讨了除米兰标准之外目前存在的其他标准，并评估了甲胎蛋白和正电子发射断层扫描在预测复发几率方面的应用。
