Cascales-Campos Pedro Antonio, Romero Pablo Ramírez, Schneider Marcel André, Lopez-Lopez Victor, Navarro José Luis, Frutos Laura, Pons Miñano Jose Antonio, Paricio Pascual Parrilla
Department of Surgery, Liver Transplantation Unit, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, Murcia, Spain.
Department of Surgery and Transplantation, University Hospital of Zurich, Zurich, Switzerland.
Eur J Radiol. 2017 Jun;91:155-159. doi: 10.1016/j.ejrad.2017.03.013. Epub 2017 Mar 23.
Hepatocellular Carcinoma (HCC) is an aggressive tumor entity, with the only curative options being surgical resection or orthotopic liver transplantation (OLT). The presence of one single tumor nodule of less than 5 centimeters diameter or a maximum of 3 nodules, with the largest of these not exceeding 3 centimeters (Milan criteria) constitute the clinical situation in which the best results for OLT in patients with HCC have been achieved. The survival of patients fulfilling the Milan criteria after transplantation is comparable to patients with similar tumor stages without cirrhosis, undergoing hepatic resection. The application of PET in oncology has become increasingly common in the last decade as it is a non-invasive tool that also gathers information about the degree of the biological aggressiveness of the tumor. The objective of this study was to perform a review of the literature, identifying the strengths and weaknesses of the PET as a prognostic tool in patients with HCC after OLT.
肝细胞癌（HCC）是一种侵袭性肿瘤实体，唯一的治愈选择是手术切除或原位肝移植（OLT）。直径小于5厘米的单个肿瘤结节或最多3个结节，其中最大的不超过3厘米（米兰标准）的情况，是在HCC患者中OLT取得最佳效果的临床情形。符合米兰标准的患者移植后的生存率与无肝硬化、处于相似肿瘤分期且接受肝切除的患者相当。在过去十年中，PET在肿瘤学中的应用越来越普遍，因为它是一种非侵入性工具，还能收集有关肿瘤生物学侵袭程度的信息。本研究的目的是对文献进行综述，确定PET作为OLT术后HCC患者预后工具的优缺点。
