Narayanan Santhosh, Prakash Divya, Subramaniam Gomathy
Dept of Cardiology, Govt. Medical College Kozhikode, India.
Dept of Pathology, Govt. Medical College Kozhikode, India.
IDCases. 2019 Jul 11;18:e00579. doi: 10.1016/j.idcr.2019.e00579. eCollection 2019.
Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case report, we present the story of an immunocompetent woman presenting as bilateral visual loss. She was found to have primary optic atrophy. Neuroimaging revealed features of chronic meningitis. Polymerase chain reaction test for Mycobacterium was positive in cerebrospinal fluid. Although secondary optic atrophy is common in the CNS TB, as a complication of meningitis, primary optic atrophy per se is infrequently reported.
视力损害是中枢神经系统结核（CNS TB）的严重并发症之一。视神经萎缩是各种形式的CNS TB的后遗症，最终导致视力损害。在CNS TB中通常发生的是继发性视神经萎缩。在本病例报告中，我们讲述了一名免疫功能正常的女性出现双侧视力丧失的故事。她被发现患有原发性视神经萎缩。神经影像学显示慢性脑膜炎的特征。脑脊液中结核分枝杆菌的聚合酶链反应检测呈阳性。虽然继发性视神经萎缩在CNS TB中很常见，是脑膜炎的并发症，但原发性视神经萎缩本身很少被报道。
