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尼泊尔喜马拉雅地区一名免疫功能正常女性的播散性肺结核:病例报告。

Disseminated tuberculosis in an immunocompetent woman from the Himalayan region of Nepal: A case report.

作者信息

Subedi Ram Chandra, Acharya Subi, Adhikari Ayush, Banmala Sabin, Shiwakoti Tibbin Kumar, Karki Pearlbiga, Gurung Shekhar, Bhatta Bhuwan, Kharbuja Naresh, Paudel Raju

机构信息

Department of Neurology Grande International Hospital Kathmandu Nepal.

Department of Pediatrics Patan Academy of Health Sciences Lalitpur Nepal.

出版信息

Clin Case Rep. 2023 Aug 2;11(8):e7754. doi: 10.1002/ccr3.7754. eCollection 2023 Aug.

DOI:10.1002/ccr3.7754
PMID:37546164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10397472/
Abstract

Disseminated tuberculosis (TB) resulting from lymphohematogenous dissemination of during primary infection or reactivation of latent disease is rare among young immunocompetent patients. Central nervous system TB (CNS TB) is one of the most challenging clinical diagnoses with high fatality. Here, we describe a young immunocompetent female with no known comorbidities initially presented with military pulmonary TB and later developed CNS TB. This presentation of disseminated TB in immunocompetent patient warrant early diagnosis and treatment.

摘要

在原发性感染期间或潜伏疾病再激活时通过淋巴血行播散导致的播散性结核病(TB)在年轻免疫功能正常的患者中很少见。中枢神经系统结核病(CNS TB)是最具挑战性的临床诊断之一,病死率很高。在此,我们描述了一名无已知合并症的年轻免疫功能正常女性,最初表现为粟粒性肺结核,后来发展为中枢神经系统结核病。免疫功能正常患者中这种播散性结核病的表现需要早期诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/c5c974317654/CCR3-11-e7754-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/5d3c65507126/CCR3-11-e7754-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/545e8e5e984f/CCR3-11-e7754-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/c5c974317654/CCR3-11-e7754-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/5d3c65507126/CCR3-11-e7754-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/545e8e5e984f/CCR3-11-e7754-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ba/10397472/c5c974317654/CCR3-11-e7754-g004.jpg

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本文引用的文献

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J Neurol. 2022 Jul;269(7):3482-3494. doi: 10.1007/s00415-022-11052-8. Epub 2022 Mar 15.
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Central nervous system tuberculosis.中枢神经系统结核。
Curr Opin Neurol. 2021 Jun 1;34(3):396-402. doi: 10.1097/WCO.0000000000000920.
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Miliary Brain Tuberculomas and Meningitis: Tuberculosis Beyond the Lungs.粟粒性脑结核瘤和脑膜炎:肺外结核病
Eur J Case Rep Intern Med. 2020 Sep 14;7(12):001931. doi: 10.12890/2020_001931. eCollection 2020.
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The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
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Disseminated Tuberculosis in a Healthy Adolescent Female.一名健康青春期女性的播散性结核病
Cureus. 2019 Jun 21;11(6):e4967. doi: 10.7759/cureus.4967.
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Review of literature on disseminated tuberculosis with emphasis on the focused diagnostic workup.关于播散性肺结核的文献综述,重点在于有针对性的诊断检查。
J Family Community Med. 2019 May-Aug;26(2):83-91. doi: 10.4103/jfcm.JFCM_106_18.
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Treatment of Tuberculous Meningitis and Its Complications in Adults.成人结核性脑膜炎及其并发症的治疗
Curr Treat Options Neurol. 2018 Feb 28;20(3):5. doi: 10.1007/s11940-018-0490-9.
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